Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3524997 | 0.79 | CYP1A2 (0.33) | TRPA1ATMTSHRALDH1A1CA1 | |
| SCHEMBL6391235 | 0.68 | — | — | |
| SCHEMBL2142605 | 0.68 | ALDH1A1 (0.42) | TRPA1HPGDALOX15RECQLHSD17B10 | |
| SCHEMBL4800808 | 0.68 | TRPA1 (0.40) | TRPA1ATMHPGDHSD17B10ALDH1A1 | |
| SCHEMBL718918 | 0.66 | CYP1A2 (0.36) | ATMHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL28942931 | 0.66 | MAPT (0.52) | TRPA1ATMHPGDALOX15RECQL | |
| SCHEMBL4802410 | 0.65 | KDM4E (0.39) | HPGDHSD17B10MAPTTSHRALDH1A1 | |
| SCHEMBL4873527 | 0.64 | TRPA1 (0.72) | TRPA1ATMHPGDALOX15RECQL | |
| SCHEMBL33721 | 0.64 | — | — | |
| SCHEMBL4802146 | 0.63 | KDM4E (0.44) | HPGDHSD17B10TDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7433118-B2 | Bridged polysesquioxane host matrices containing lanthanides chelated by organic guest ligands, and methods of making such matrices | LUCENT TECHNOLOGIES INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-20040263952-A1 | Bridged polysesquioxane host matrices containing lanthanides chelated by organic guest ligands, and methods of making such matrices | LUCENT TECHNOLOGIES, INC. (US) | 2004-12-30 | — | — | US | disclosed |