SCHEMBL4802410

SCHEMBL4802410

Cc1[c]c2ccccc2c(O)c1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.39
HTT P42858 3/20 0.36
LMNA P02545 2/20 0.36
DAO P14920 1/20 0.35
DDO Q99489 1/20 0.35
PKM P14618 1/20 0.34
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
USP2 O75604 1/20 0.33
TNNI3 P19429 1/20 0.33
TNNT2 P45379 1/20 0.33
TNNC1 P63316 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP1A2 P05177 2/20 0.32
IDO1 P14902 1/20 0.32
ALDH1A1 P00352 3/20 0.31
GAA P10253 2/20 0.31
GLA P06280 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL718918 0.80 CYP1A2 (0.36) CYP1A2ALDH1A1HPGDCYP2C19HSD17B10
SCHEMBL4574784 0.77 IDO1 (0.41) KDM4EHTTLMNAPKMMEN1
SCHEMBL1396389 0.73 IDO1 (0.38) KDM4EHTTLMNAPKMMEN1
SCHEMBL4802412 0.72 CYP1A2 (0.35) KDM4EHTTLMNADAODDO
SCHEMBL14959192 0.72 HTT (0.38) KDM4EHTTLMNADAODDO
SCHEMBL2336588 0.72 CYP1A2 (0.41) KDM4EHTTLMNAMAPTSMN1; SMN2
SCHEMBL3244018 0.71 LMNA (0.54) KDM4EHTTLMNADAODDO
SCHEMBL6048372 0.69 ACHE (0.39) LMNACYP1A2ALDH1A1TSHR
SCHEMBL9716925 0.67 LMNA (0.50) KDM4EHTTLMNADAODDO
SCHEMBL27705068 0.67 LMNA (0.50) KDM4EHTTLMNADAODDO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7433118-B2 Bridged polysesquioxane host matrices containing lanthanides chelated by organic guest ligands, and methods of making such matrices LUCENT TECHNOLOGIES INC. (US) 2008-10-07 US disclosed
US-20040263952-A1 Bridged polysesquioxane host matrices containing lanthanides chelated by organic guest ligands, and methods of making such matrices LUCENT TECHNOLOGIES, INC. (US) 2004-12-30 US disclosed
US-20020196896-A1 Exposure method, exposure apparatus, X-ray mask, semiconductor device and microstructure MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2002-12-26 US disclosed
EP-1193553-A2 Exposure method, exposure apparatus, x-ray mask, semiconductor device and microstructure MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2002-04-03 EP disclosed