SCHEMBL480087

SCHEMBL480087

CCC(=O)Oc1ccc(CBr)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
ESR1 P03372 2/20 0.59
HIF1A Q16665 2/20 0.59
RECQL P46063 1/20 0.59
ELANE P08246 2/20 0.54
ACHE P22303 2/20 0.46
MAPT P10636 3/20 0.46
LMNA P02545 2/20 0.46
HTT P42858 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 1/20 0.46
RAB9A P51151 3/20 0.44
ALOX15 P16050 1/20 0.44
NPC1 O15118 2/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
THRB P10828 1/20 0.42
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL312147 0.85 KMT2A (0.76) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL6242335 0.85 BCL9 (0.57) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL1512672 0.84 KMT2A (0.63) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL11445596 0.83 KMT2A (0.73) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL170186 0.82 KMT2A (0.61) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL27902979 0.82 KMT2A (0.61) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL11239940 0.81 THRB (0.40) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL2333877 0.81 KMT2A (0.59) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL20593516 0.81 THRB (0.64) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL27324289 0.81 KMT2A (0.59) KMT2ASMN1; SMN2ESR1HIF1ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116354814-A Processing technology for improving purity of p-bromomethylphenyl propionic acid 贵州天豪民族药业有限公司 2023-06-30 CN claimed
CN-115710173-A Preparation method of p-bromomethylphenyl propionic acid 贵州天豪民族药业有限公司 2023-02-24 CN claimed
CN-108586233-B Method for synthesizing 2- (4' -bromomethylphenyl) propionate 湖北迅达药业股份有限公司 2021-05-18 CN claimed
CN-112473593-A Automatic production line of 2-4 bromomethyl phenyl propionic acid 贵州天豪民族药业有限公司 2021-03-12 CN claimed
CN-116354814-A Processing technology for improving purity of p-bromomethylphenyl propionic acid 贵州天豪民族药业有限公司 2023-06-30 CN disclosed
CN-116354814-A Processing technology for improving purity of p-bromomethylphenyl propionic acid 贵州天豪民族药业有限公司 2023-06-30 CN disclosed
CN-116354814-A Processing technology for improving purity of p-bromomethylphenyl propionic acid 贵州天豪民族药业有限公司 2023-06-30 CN disclosed
CN-115710173-A Preparation method of p-bromomethylphenyl propionic acid 贵州天豪民族药业有限公司 2023-02-24 CN disclosed
CN-115710173-A Preparation method of p-bromomethylphenyl propionic acid 贵州天豪民族药业有限公司 2023-02-24 CN disclosed
CN-115710173-A Preparation method of p-bromomethylphenyl propionic acid 贵州天豪民族药业有限公司 2023-02-24 CN disclosed
CN-108586233-B Method for synthesizing 2- (4' -bromomethylphenyl) propionate 湖北迅达药业股份有限公司 2021-05-18 CN disclosed
CN-112473593-A Automatic production line of 2-4 bromomethyl phenyl propionic acid 贵州天豪民族药业有限公司 2021-03-12 CN disclosed
EP-1150673-A4 MONO-ACYLOXY ARALKYL NEUROMUSCULAR RELAXANTS NEWLAXANT L L C (US) 2002-04-24 EP disclosed
CN-1338934-A Mono-acyloxy aralkyl neuronuscular relaxants NEWLAXANT L L C (US) 2002-03-06 CN disclosed
EP-1150673-A1 MONO-ACYLOXY ARALKYL NEUROMUSCULAR RELAXANTS Newlaxant, L.L.C. (US) 2001-11-07 EP disclosed
US-6313166-B1 USED FOR PEST CONTROL, AS MICROBICIDES, INSECTICIDES AND ACARICIDES IN AGRICULTURE, HORTICULTURE AND IN HYGIENE SECTOR BAYER AKTIENGESELLSCHAFT (DE) 2001-11-06 US disclosed
WO-2000044377-A1 MONO-ACYLOXY ARALKYL NEUROMUSCULAR RELAXANTS NEWLAXANT, L.L.C. (US) 2000-08-03 WO disclosed
US-5981585-A MICROBICIDES, INSECTICIDES AND ACARICIDES IN AGRICULTURE, HORTICULTURE AND IN THE HYGIENE SECTOR NOVARTIS FINANCE CORPORATION (US) 1999-11-09 US disclosed
US-5756426-A Phenyl acetic acid derivatives as pesticides NOVARTIS CORPORATION (US) 1998-05-26 US disclosed
EP-0319316-A2 Griseolic acid monoesters, their preparation and use SANKYO COMPANY LIMITED (JP) 1989-06-07 EP disclosed