Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | ELANE | P08246 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312147 | 0.85 | KMT2A (0.76) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL1512672 | 0.84 | KMT2A (0.63) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL11445596 | 0.83 | KMT2A (0.73) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL27902979 | 0.82 | KMT2A (0.61) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL170186 | 0.82 | KMT2A (0.61) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL27324289 | 0.81 | KMT2A (0.59) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL480087 | 0.81 | KMT2A (0.59) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL20593516 | 0.81 | THRB (0.64) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL197418 | 0.80 | KMT2A (0.63) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL9799923 | 0.80 | KMT2A (0.63) | KMT2ASMN1; SMN2ESR1HIF1ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100376242-C | 2-aryl-propionic acid and medicine composition containing same | DOMPAY CO LTD (IT) | 2008-03-26 | — | — | CN | claimed |
| CN-1612729-A | 2-Aryl-propionic acids and pharmaceutical compositions containing them | DOMPAY CO LTD (IT) | 2005-05-04 | — | — | CN | claimed |
| WO-2021005167-A1 | LIGANDS FOR CAPTURING MICROVESICLES AND USES THEREOF | UNIVERSITÉ DE BORDEAUX (FR) | 2021-01-14 | — | — | WO | disclosed |
| CN-106349051-A | Preparation method of methyl 2-(4-chloromethylphenyl)propionate | 宁波博撷化学科技有限公司 | 2017-01-25 | — | — | CN | disclosed |
| EP-1940818-B1 | AMINOACID DERIVATIVES CONTAINING A DISULFANYL GROUP IN THE FORM OF MIXED DISULFANYL AND AMINOPEPTIDASE N INHIBITORS | PHARMALEADS (FR) | 2011-08-24 | — | — | EP | disclosed |
| EP-1940818-A1 | AMINOACID DERIVATIVES CONTAINING A DISULFANYL GROUP IN THE FORM OF MIXED DISULFANYL AND AMINOPEPTIDASE N INHIBITORS | Pharmaleads (FR) | 2008-07-09 | — | — | EP | disclosed |
| CN-100376242-C | 2-aryl-propionic acid and medicine composition containing same | DOMPAY CO LTD (IT) | 2008-03-26 | — | — | CN | disclosed |
| WO-2007048787-A1 | AMINOACID DERIVATIVES CONTAINING A DISULFANYL GROUP IN THE FORM OF MIXED DISULFANYL AND AMINOPEPTIDASE N INHIBITORS | PHARMALEADS (FR) | 2007-05-03 | — | — | WO | disclosed |
| CN-1612729-A | 2-Aryl-propionic acids and pharmaceutical compositions containing them | DOMPAY CO LTD (IT) | 2005-05-04 | — | — | CN | disclosed |
| EP-1150673-A4 | MONO-ACYLOXY ARALKYL NEUROMUSCULAR RELAXANTS | NEWLAXANT L L C (US) | 2002-04-24 | — | — | EP | disclosed |
| CN-1338934-A | Mono-acyloxy aralkyl neuronuscular relaxants | NEWLAXANT L L C (US) | 2002-03-06 | — | — | CN | disclosed |
| EP-1150673-A1 | MONO-ACYLOXY ARALKYL NEUROMUSCULAR RELAXANTS | Newlaxant, L.L.C. (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000044377-A1 | MONO-ACYLOXY ARALKYL NEUROMUSCULAR RELAXANTS | NEWLAXANT, L.L.C. (US) | 2000-08-03 | — | — | WO | disclosed |