SCHEMBL170186

SCHEMBL170186

CCC(=O)Oc1ccc(CO)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.61
ESR1 P03372 2/20 0.61
HIF1A Q16665 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
RECQL P46063 1/20 0.61
ELANE P08246 2/20 0.56
PPARG P37231 1/20 0.49
PPARA Q07869 1/20 0.49
ACHE P22303 2/20 0.47
THRB P10828 2/20 0.47
LMNA P02545 2/20 0.47
HTT P42858 2/20 0.47
MAPT P10636 2/20 0.47
ALDH1A1 P00352 1/20 0.47
HSD17B10 Q99714 1/20 0.47
RAB9A P51151 2/20 0.46
ALOX15 P16050 1/20 0.45
NPC1 O15118 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL312147 0.87 KMT2A (0.76) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL1512672 0.86 KMT2A (0.63) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL11445596 0.85 KMT2A (0.73) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL9332754 0.85 KMT2A (0.58) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL8387984 0.85 BCL9 (0.58) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL27902979 0.84 KMT2A (0.61) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL18613655 0.83 KMT2A (0.61) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL2333877 0.82 KMT2A (0.59) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL20593516 0.82 THRB (0.64) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL27324289 0.82 KMT2A (0.59) KMT2AESR1HIF1ASMN1; SMN2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340916-A1 METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-11-06 US disclosed
US-12391971-B2 Method for synthesizing peptides in cell-free translation system CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-19 US disclosed
US-20240066133-A1 THERAPEUTIC AGENTS AND CONJUGATES THEREOF AJ SCIENCES (YIXING) CO., LTD (CN) 2024-02-29 US disclosed
US-11857635-B2 Linker compound, polyethylene glycol-linker conjugate and derivative thereof and polyethylene glycol-linker-drug conjugate JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) 2024-01-02 US disclosed
WO-2023226965-A1 ROCK INHIBITORS AND USES THEREOF DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2023-11-30 WO disclosed
US-20200040372-A1 METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2020-02-06 US disclosed
US-20200040372-A1 METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2020-02-06 US disclosed
WO-2018143145-A1 METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM 中外製薬株式会社 2018-08-09 WO disclosed
CN-107567445-A It can be used as 2 phenyl 3H imidazos [4,5 B] pyridine derivates of mammal EGFR-TK ROR1 activities inhibitor 坎塞拉有限公司 2018-01-09 CN disclosed
EP-2428577-B1 Preparation of tyrosinase-inhibiting hydroxybenzyl and hydroxypyranonemethyl esters EASTMAN CHEM CO (US) 2014-01-22 EP disclosed
US-4138397-A BACTERICIDES RICHARDSON-MERRELL INC. (US) 1979-02-06 US disclosed
US-4122260-A CONTAINING FORMYL SUBSTITUTED PYRROLE, ANTIBIOTICS YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1978-10-24 US disclosed
US-4118562-A ANTIBIOTICS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1978-10-03 US disclosed
US-4093804-A ANTIBIOTICS YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1978-06-06 US disclosed
US-4093802-A ANTIBIOTICS YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1978-06-06 US disclosed
US-4045438-A Cephalosporin antibiotics YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1977-08-30 US disclosed
US-4031083-A Cephalosporin antibiotics YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1977-06-21 US disclosed
US-4026887-A Cephalosporin antibiotics YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) 1977-05-31 US disclosed
US-3994875-A CEPHALOSPORINS, PENICILLINS YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) 1976-11-30 US disclosed
US-3948904-A ANTIBIOTICS YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200040372-A1 METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM AARS1, NSUN3, RNGTT KMT2A 1543/4885ESR1 3999/4885HIF1A 3438/4885
US-12391971-B2 Method for synthesizing peptides in cell-free translation system AARS1, NSUN3, RNGTT KMT2A 1543/4885ESR1 3999/4885HIF1A 3438/4885
US-20240066133-A1 THERAPEUTIC AGENTS AND CONJUGATES THEREOF TLR9, STING1, TLR3 KMT2A 812/4885ESR1 546/4885HIF1A 2110/4885
US-11857635-B2 Linker compound, polyethylene glycol-linker conjugate and derivative thereof and polyethylene glycol-linker-drug conjugate DCLRE1A, LANCL2, SI KMT2A 1190/4885ESR1 1495/4885HIF1A 2489/4885
US-20250340916-A1 METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM AARS1, NSUN3, RNGTT KMT2A 1543/4885ESR1 3999/4885HIF1A 3438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.