Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 9/20 | 0.45 |
| ▸ | CTSK | P43235 | 8/20 | 0.45 |
| ▸ | CTSB | P07858 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801162 | 1.00 | ACE (0.52) | ACEITGB3ITGA2BPTPN1ITGB1 | |
| SCHEMBL4801481 | 0.87 | ACE (0.52) | ACEITGB3ITGA2BPTPN1ITGB1 | |
| SCHEMBL4739186 | 0.87 | ACE (0.52) | ACEITGB3ITGA2BPTPN1ITGB1 | |
| SCHEMBL1217701 | 0.87 | ALOX15 (0.57) | ACEITGB3ITGA2BPTPN1ITGB1 | |
| SCHEMBL27406863 | 0.86 | ACE (0.56) | ACEITGB3ITGA2BPTPN1ITGB1 | |
| SCHEMBL1216618 | 0.85 | ACE (0.55) | ACEITGB3ITGA2BPTPN1ITGB1 | |
| Hydrochloric Acid SCHEMBL1214885 | 0.84 | ACE (0.54) | ACEITGB3ITGA2BPTPN1ITGB1 | |
| SCHEMBL1211350 | 0.83 | ALOX15 (0.38) | ACEITGB3ITGA2BPTPN1ITGB1 | |
| SCHEMBL29726545 | 0.82 | LDHA (0.58) | ACEITGB3ITGA2BPTPN1ITGB1 | |
| SCHEMBL2675545 | 0.82 | LDHA (0.58) | ACEITGB3ITGA2BPTPN1ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324273-B2 | Catechol protected levodopa diester prodrugs, compositions, and methods of use | XENOPORT, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20080171789-A1 | Catechol protected levodopa diester prodrugs, compositions, and methods of use | XENOPORT, INC. | 2008-07-17 | — | — | US | disclosed |
| WO-2008079387-A1 | CATECHOL PROTECTED LEVODOPA DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE | XENOPORT, INC. (US) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171789-A1 | Catechol protected levodopa diester prodrugs, compositions, and methods of use | COMT, PARK7, DDT | ACE 245/4885ITGB3 4675/4885ITGA2B 4736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.