Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27488382 | 0.81 | ALDH1A1 (0.59) | ADAMTS4HTR2AHTR2CHTR7L3MBTL1 | |
| SCHEMBL4802102 | 0.79 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1HTTTDP1MAPK1 | |
| SCHEMBL8973925 | 0.78 | KMT2A (0.49) | ALDH1A1KDM4ETDP1MAPK1 | |
| SCHEMBL27561487 | 0.73 | SMN1; SMN2 (0.69) | ADAMTS4L3MBTL1ALDH1A1MMP9MMP8 | |
| SCHEMBL2993376 | 0.72 | ALDH1A1 (0.67) | L3MBTL1ALDH1A1HTTTDP1MAPK1 | |
| SCHEMBL9734100 | 0.71 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL28470101 | 0.70 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL18758786 | 0.69 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1POLBTDP1SMN1; SMN2 | |
| SCHEMBL28472152 | 0.68 | ALDH1A1 (0.56) | ALDH1A1POLBTDP1SMN1; SMN2 | |
| SCHEMBL8973579 | 0.68 | ALDH1A1 (0.56) | ALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008030120-A1 | A METHOD FOR THE FLUORESCENT DETECTION OF NITROREDUCTASE ACTIVITY USING NITRO-SUBSTITUTED AROMATIC COMPOUNDS | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-03-13 | — | — | WO | claimed |