Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | HTR2C | P28335 | 3/20 | 0.58 |
| ▸ | HTR7 | P34969 | 3/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27561487 | 0.84 | SMN1; SMN2 (0.69) | ALDH1A1L3MBTL1MMP9MMP8MMP13 | |
| SCHEMBL8622042 | 0.84 | MMP9 (0.71) | ALDH1A1SLC1A3SLC1A2SLC1A1MMP9 | |
| SCHEMBL8993739 | 0.84 | MMP9 (0.71) | ALDH1A1SLC1A3SLC1A2SLC1A1MMP9 | |
| SCHEMBL13588618 | 0.83 | SMN1; SMN2 (0.68) | ALDH1A1HTR2AHTR2CHTR7SLC1A3 | |
| SCHEMBL9942053 | 0.83 | ALDH1A1 (0.72) | ALDH1A1HTR2AHTR2CHTR7SLC1A3 | |
| SCHEMBL9148226 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HTR2AHTR2CHTR7SLC1A3 | |
| SCHEMBL9356821 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HTR2AHTR2CHTR7SLC1A3 | |
| SCHEMBL4802117 | 0.81 | ADAMTS4 (0.41) | ALDH1A1HTR2AHTR2CHTR7L3MBTL1 | |
| SCHEMBL3692115 | 0.80 | L3MBTL1 (0.58) | ALDH1A1HTR2AHTR2CHTR7SLC1A3 | |
| SCHEMBL5277171 | 0.80 | ALDH1A1 (0.52) | ALDH1A1SLC1A3SLC1A2SLC1A1LARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1164232-A | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | ZENECA LTD (GB) | 1997-11-05 | — | — | CN | disclosed |