SCHEMBL8973579

SCHEMBL8973579

O=[N+]([O-])c1cccc2cc(S(=O)(=O)Cl)ccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TDP1 Q9NUW8 3/20 0.48
TSHR P16473 1/20 0.46
HPRT1 P00492 1/20 0.45
NCOA1 Q15788 1/20 0.42
NCOA3 Q9Y6Q9 1/20 0.42
VCAM1 P19320 4/20 0.41
CASP6 P55212 1/20 0.41
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
CYP3A4 P08684 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
PDE10A Q9Y233 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
GPR35 Q9HC97 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23909572 0.87 ALDH1A1 (0.56) ALDH1A1TDP1TSHRHPRT1NCOA1
SCHEMBL11051233 0.85 VCAM1 (0.45) ALDH1A1TDP1TSHRHPRT1VCAM1
SCHEMBL9734100 0.84 ALDH1A1 (0.56) ALDH1A1TDP1TSHRHPRT1CASP6
SCHEMBL14058836 0.84 CA2 (0.58) ALDH1A1TDP1TSHRVCAM1MAPT
SCHEMBL28472152 0.84 ALDH1A1 (0.56) ALDH1A1TDP1TSHRHPRT1NCOA1
SCHEMBL28470101 0.83 ALDH1A1 (0.54) ALDH1A1TDP1TSHRHPRT1CASP6
SCHEMBL11696487 0.78 ALDH1A1 (0.61) ALDH1A1TDP1TSHRHPRT1VCAM1
SCHEMBL3813276 0.77 VCAM1 (0.50) ALDH1A1TSHRVCAM1CASP6KMT2A
SCHEMBL9735773 0.77 ALDH1A1 (0.69) ALDH1A1TDP1TSHRHPRT1CASP6
SCHEMBL8668528 0.76 TSHR (0.66) ALDH1A1TDP1TSHRHPRT1CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113527680-B Polymer, photosensitive resin composition, pattern forming method, cured film, and electronic component 信越化学工业株式会社 2023-04-28 CN disclosed
EP-3896521-B1 POLYMER, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD, METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT SHINETSU CHEMICAL CO (JP) 2022-12-14 EP disclosed
US-11333975-B2 Polymer, photosensitive resin composition, patterning method, method of forming cured film, interlayer insulating film, surface protective film, and electronic component INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2022-05-17 US disclosed
CN-113527680-A Polymer, photosensitive resin composition, pattern forming method, cured film, and electronic component 信越化学工业株式会社 2021-10-22 CN disclosed
EP-3896521-A1 POLYMER, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD, METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT Shin-Etsu Chemical Co., Ltd. (JP) 2021-10-20 EP disclosed
US-20210317268-A1 POLYMER, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD, METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-10-14 US disclosed
EP-2705011-B1 NOVEL PRECURSORS OF GLUTAMATE DERIVATIVES PIRAMAL IMAGING SA (CH) 2016-08-17 EP disclosed
US-9000037-B2 Precursors of glutamate derivatives PIRAMAL IMAGING SA (CH) 2015-04-07 US disclosed
US-20140243532-A1 NOVEL PRECURSORS OF GLUTAMATE DERIVATIVES PIRAMAL IMAGING SA (CH) 2014-08-28 US disclosed
CN-103930388-A Novel precursors of glutamate derivatives Bayer Pharma AG 2014-07-16 CN disclosed
US-RE35279-E ALDOSE REDUCTASE INHIBITORS MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1996-06-18 US disclosed
US-5202339-A Hypoglycemic, hypolipedemic agents MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1993-04-13 US disclosed
EP-0305947-B1 HYDANTOIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS THEIR USE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1992-07-29 EP disclosed
US-5004751-A Antidiabetic agents; aldoe reductase inhibitors MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1991-04-02 US disclosed
EP-0163854-B1 PROCESS FOR THE ELIMINATION OF FLUORESCENCE AND CATIONIC OR AMPHOTERIC AROMATIC NITRO COMPOUNDS BAYER AG (DE) 1991-02-27 EP disclosed
US-4914099-A TREATMENT OR PREVENTION OF DIABETIC COMPLICATIONS MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1990-04-03 US disclosed
WO-1989001934-A1 HYDANTOIN DERIVATIVES MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1989-03-09 WO disclosed
EP-0305947-A1 Hydantoin derivatives, process for their preparation and pharmaceutical compositions containing the same as well as their use MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1989-03-08 EP disclosed
US-4695405-A Process for quenching fluorescence, and new cationic or amphoteric aromatic nitro compounds BAYER AKTIENGESELLSCHAFT (DE) 1987-09-22 US disclosed
EP-0163854-A2 Process for the elimination of fluorescence and cationic or amphoteric aromatic nitro compounds BAYER AG (DE) 1985-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140243532-A1 NOVEL PRECURSORS OF GLUTAMATE DERIVATIVES GLUL, GRIN1, SLC7A11 ALDH1A1 1854/4885TDP1 3346/4885TSHR 1754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.