SCHEMBL4802412

SCHEMBL4802412

Cc1c(O)[c]c2ccccc2c1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.35
CYP2A6 P11509 2/20 0.35
TSHR P16473 2/20 0.35
IDO1 P14902 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
KDM4E B2RXH2 1/20 0.32
DAO P14920 1/20 0.32
DDO Q99489 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP1 P29466 1/20 0.32
RAB9A P51151 1/20 0.32
CASP7 P55210 1/20 0.32
ATM Q13315 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2336588 0.79 CYP1A2 (0.41) CYP1A2CYP2A6TSHRLMNAHTT
SCHEMBL718918 0.77 CYP1A2 (0.36) CYP1A2CYP2A6TSHRALDH1A1L3MBTL1
SCHEMBL1396389 0.75 IDO1 (0.38) CYP1A2IDO1LMNAHTTALDH1A1
SCHEMBL4802410 0.72 KDM4E (0.39) CYP1A2CYP2A6TSHRIDO1LMNA
SCHEMBL4800808 0.71 TRPA1 (0.40) CYP1A2CYP2A6ALDH1A1KDM4EHPGD
SCHEMBL4876788 0.71 ALDH1A1 (0.46) CYP1A2HTTALDH1A1KDM4EHPGD
SCHEMBL2455965 0.71 CYP1A2 (0.31) CYP1A2TSHRL3MBTL1CYP3A4HPGD
SCHEMBL3434527 0.70 CA12 (0.39) TSHRIDO1LMNAALDH1A1L3MBTL1
SCHEMBL9638552 0.70 IDO1 (0.35) CYP1A2TSHRIDO1LMNAHTT
SCHEMBL4574784 0.69 IDO1 (0.41) CYP1A2IDO1LMNAHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7433118-B2 Bridged polysesquioxane host matrices containing lanthanides chelated by organic guest ligands, and methods of making such matrices LUCENT TECHNOLOGIES INC. (US) 2008-10-07 US disclosed
US-20040263952-A1 Bridged polysesquioxane host matrices containing lanthanides chelated by organic guest ligands, and methods of making such matrices LUCENT TECHNOLOGIES, INC. (US) 2004-12-30 US disclosed
US-20020196896-A1 Exposure method, exposure apparatus, X-ray mask, semiconductor device and microstructure MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2002-12-26 US disclosed
EP-1193553-A2 Exposure method, exposure apparatus, x-ray mask, semiconductor device and microstructure MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2002-04-03 EP disclosed