SCHEMBL2336588

SCHEMBL2336588

Cc1c2ccccc2[c]c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.41
TSHR P16473 5/20 0.38
CYP3A4 P08684 3/20 0.38
HSD17B10 Q99714 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MAPK1 P28482 2/20 0.38
HIF1A Q16665 2/20 0.38
ATM Q13315 2/20 0.38
HPGD P15428 2/20 0.38
CASP1 P29466 1/20 0.38
RAB9A P51151 1/20 0.38
CASP7 P55210 1/20 0.38
CYP2A6 P11509 6/20 0.37
AHR P35869 1/20 0.36
ALDH1A1 P00352 4/20 0.35
ACHE P22303 2/20 0.33
NPC1 O15118 1/20 0.32
HSP90AA1 P07900 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL718918 0.82 CYP1A2 (0.36) CYP1A2TSHRCYP3A4HSD17B10L3MBTL1
SCHEMBL4802412 0.79 CYP1A2 (0.35) CYP1A2TSHRCYP3A4HSD17B10L3MBTL1
SCHEMBL6759020 0.77 CYP2A6 (0.33) CYP1A2TSHRHSD17B10CYP2A6ALDH1A1
SCHEMBL2455965 0.75 CYP1A2 (0.31) CYP1A2TSHRCYP3A4HSD17B10L3MBTL1
SCHEMBL29379467 0.75 CYP1A2 (0.56) CYP1A2TSHRCYP3A4HSD17B10L3MBTL1
SCHEMBL377040 0.75 CYP1A2 (0.56) CYP1A2TSHRCYP3A4HSD17B10L3MBTL1
SCHEMBL4574784 0.72 IDO1 (0.41) CYP1A2CYP3A4HSD17B10L3MBTL1HIF1A
SCHEMBL15352116 0.72 ALDH1A1 (0.30) TSHRHSD17B10CYP2A6ALDH1A1TDP1
SCHEMBL2255389 0.72 ALDH1A1 (0.44) CYP1A2TSHRCYP3A4HSD17B10HIF1A
SCHEMBL1616278 0.72 MAOA (0.44) CYP1A2TSHRHSD17B10HIF1ACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55157558-A None JP disclosed
CN-115671088-A Application of (10-methyl-9-anthryl) thioamino imino acid methyl ester and derivative in preparation of medicine for treating pulmonary fibrosis 华中科技大学 2023-02-03 CN disclosed
CN-115671088-A Application of (10-methyl-9-anthryl) thioamino imino acid methyl ester and derivative in preparation of medicine for treating pulmonary fibrosis 华中科技大学 2023-02-03 CN disclosed
CN-103091986-B Positive-type photosensitive resin composition, cured film and forming method thereof, liquid crystal display device and organic electroluminescence display device and method of manufacturing same 富士胶片株式会社 2018-05-18 CN disclosed
EP-2818462-B1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMISCENT ELEMENT CONTAINING THESE AS COMPONENT TOSOH CORP (JP) 2017-11-08 EP disclosed
US-9624193-B2 Cyclic azine derivatives, processes for producing these, and organic electroluminescent element containing these as component TOSOH CORPORATION (JP) 2017-04-18 US disclosed
US-20150329544-A1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT TOSOH CORPORATION (JP) 2015-11-19 US disclosed
US-20150311453-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ILLUMINATION DEVICE PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2015-10-29 US disclosed
US-9120773-B2 Cyclic azine derivatives, processes for producing these, and organic electroluminescent element containing these as component TOSOH CORPORATION (JP) 2015-09-01 US disclosed
EP-2818462-A1 Cyclic azine derivatives, processes for producing these, and organic electrolumiscent element containing these as component TOSOH CORPORATION (JP) 2014-12-31 EP disclosed
EP-2360752-A1 ORGANIC ELECTROLUMINESCENT ELEMENT FUJIFILM Corporation (JP) 2011-08-24 EP disclosed
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same JNC CORPORATION (JP) 2010-02-04 US disclosed
US-20060293503-A1 Polyaminopyridines and method for producing same SUMITOMO SEIKA CHEMICALS CO., LTD (JP) 2006-12-28 US disclosed
CN-1811430-A Singlet oxygen europium coordination compound fluorescent probe and application thereof DALIAN INST OF CHEMICAL PHSICS (CN) 2006-08-02 CN disclosed
EP-1669390-A1 POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-06-14 EP disclosed
US-20060110622-A1 Organic electroluminescent device LG ELECTRONICS, INC. (KR) 2006-05-25 US disclosed
CN-1735301-A Organic electroluminescent device LG ELECTRONICS INC (KR) 2006-02-15 CN disclosed
EP-1624501-A2 Organic electroluminescent device LG Electronics, Inc. (KR) 2006-02-08 EP disclosed
US-4263394-A Aqueous alkaline soluble photopolymerizable material VICKERS LIMITED (GB) 1981-04-21 US disclosed
JP-S55157558-A MONOAMIDINOHYDRAZONE OF TRICYCLIC CARBONYL COMPOUND AND ITS PREPARATION NISHIMURA TAMIO 1980-12-08 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150329544-A1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT CPNE4, EPB41, AZI2 CYP1A2 1801/4885TSHR 2974/4885CYP3A4 2522/4885
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same TRPV3, TRPC3, HVCN1 CYP1A2 1391/4885TSHR 3646/4885CYP3A4 1505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.