Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1771602 | 0.92 | ALDH1A1 (0.48) | MPOALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL4802603 | 0.84 | MPO (0.60) | MPOALDH1A1ABCB1ELANE | |
| SCHEMBL6858889 | 0.81 | MPO (0.57) | MPOALDH1A1MAPTSMN1; SMN2ELANE | |
| SCHEMBL14267917 | 0.80 | MPO (0.56) | MPOMAPTABCB1ELANE | |
| SCHEMBL7495315 | 0.79 | MPO (0.49) | MPOALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL6112988 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MAPTMAPK1SMN1; SMN2ABCB1 | |
| SCHEMBL14463046 | 0.78 | GAA (0.38) | ALDH1A1 | |
| SCHEMBL5201088 | 0.78 | MAOA (0.49) | — | |
| SCHEMBL6112977 | 0.77 | MIF (0.48) | — | |
| SCHEMBL6113173 | 0.77 | TUBB4A (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3836910-A1 | BENZOSUBERENE ANALOGUES AND RELATED COMPOUNDS WITH ACTIVITY AS ANTICANCER AGENTS | Baylor University (US) | 2021-06-23 | — | — | EP | disclosed |
| WO-2020037209-A1 | BENZOSUBERENE ANALOGUES AND RELATED COMPOUNDS WITH ACTIVITY AS ANTICANCER AGENTS | BAYLOR UNIVERSITY (US) | 2020-02-20 | — | — | WO | disclosed |
| EP-1263763-B1 | TUBULIN BINDING LIGANDS | UNIV BAYLOR (US) | 2007-07-25 | — | — | EP | disclosed |
| EP-1263763-A2 | TUBULIN BINDING LIGANDS AND CORRESPONDING PRODRUG CONSTRUCTS | BAYLOR UNIVERSITY (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001068654-A2 | TUBULIN BINDING LIGANDS AND CORRESPONDING PRODRUG CONSTRUCTS | BAYLOR UNIVERSITY (US) | 2001-09-20 | — | — | WO | disclosed |