SCHEMBL4803231

SCHEMBL4803231

CC1=CC(=C(C#N)C#N)C=CO1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14234322 0.76
SCHEMBL1097940 0.74 ALDH1A1 (0.42) ALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL170080 0.69
Trimethylammonium SCHEMBL28460569 0.67
SCHEMBL3424457 0.65 ALDH1A1 (0.36) ALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL27537779 0.64 ALDH1A1 (0.35) ALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL7629212 0.64
SCHEMBL30195681 0.64 MEN1 (0.30) ALDH1A1KMT2A
SCHEMBL10412429 0.63 ALDH1A1 (0.34) ALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL10775564 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180652-B Preparation process of benzopyran nitrile fluorescent probe molecule for detecting Cys 曲靖师范学院 2021-12-14 CN claimed
CN-109180652-B Preparation process of benzopyran nitrile fluorescent probe molecule for detecting Cys 曲靖师范学院 2021-12-14 CN disclosed
EP-3466937-B1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR AND IMAGING DEVICE CANON KK (JP) 2021-03-24 EP disclosed
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device CANON KABUSHIKI KAISHA (JP) 2021-03-16 US disclosed
WO-2021045178-A1 ORGANIC THIN FILM AND METHOD FOR PRODUCING ORGANIC THIN FILM, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, LIGHTING DEVICE, ORGANIC THIN FILM SOLAR CELL, PHOTOELECTRIC CONVERSION ELEMENT, THIN FILM TRANSISTOR, COATING COMPOSITION AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS 日本放送協会 2021-03-11 WO disclosed
WO-2021045179-A1 ORGANIC THIN FILM, METHOD FOR PRODUCING ORGANIC THIN FILM, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, LIGHTING DEVICE, ORGANIC THIN FILM SOLAR CELL, THIN FILM TRANSISTOR, PHOTOELECTRIC CONVERSION ELEMENT, COATING COMPOSITION AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS 日本放送協会 2021-03-11 WO disclosed
CN-110642845-B Quinoline derivative and application thereof 中国人民解放军军事科学院军事医学研究院 2021-01-05 CN disclosed
US-10861903-B2 Organic compound and photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2020-12-08 US disclosed
CN-110642845-A Quinoline derivative and application thereof 中国人民解放军军事科学院军事医学研究院 2020-01-03 CN disclosed
EP-3466937-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR AND IMAGING DEVICE C/o Canon Kabushiki Kaisha (JP) 2019-04-10 EP disclosed
US-6649089-B2 Red fluorescent material as dopes E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2003-11-18 US disclosed
US-20030193043-A1 RED ORGANIC ELECTROLUMINESCENT MATERIALS E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2003-10-16 US disclosed
US-20030180574-A1 Efficient organic electroluminescent devices with red fluorescent dopants E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2003-09-25 US disclosed
WO-2003078542-A1 RED ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME NEOVIEW CO., LTD. (KR) 2003-09-25 WO disclosed
US-20030099861-A1 Efficient red organic electroluminescent devices CITYU RESEARCH LTD. (HK) 2003-05-29 US disclosed
US-6455579-B1 Pyran derivatives KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2002-09-24 US disclosed
EP-1234866-A2 Organic, especially red electroluminescent device and doping agents Syntec Gesellschaft für Chemie und Technologie der Informationsaufzeichnung mbH (DE) 2002-08-28 EP disclosed
EP-1078926-A9 PYRAN DERIVATIVES Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2001-05-02 EP disclosed
JP-2001081090-A PYRAN DERIVATIVE HAYASHIBARA BIOCHEM LAB INC 2001-03-27 JP disclosed
EP-1078926-A1 PYRAN DERIVATIVES Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2001-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10861903-B2 Organic compound and photoelectric conversion element NR2E3, CRY1, CRY2 ALDH1A1 569/4885KDM4E 2334/4885SMN1; SMN2 3079/4885
US-20030193043-A1 RED ORGANIC ELECTROLUMINESCENT MATERIALS IK, RCN1, MRPL21 ALDH1A1 53/4885KDM4E 2694/4885SMN1; SMN2 3058/4885
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device NR2E3, CRY2, GPR3 ALDH1A1 602/4885KDM4E 2895/4885SMN1; SMN2 1807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.