SCHEMBL4803323

SCHEMBL4803323

CCCOC1CC(C)(CC)N(OC(C)c2ccccc2)C(C)(CC)C1C

nearest known ligand 0.31

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.31
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31
OPRK1 P41145 1/20 0.31
OPRL1 P41146 1/20 0.31
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
NTSR1 P30989 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5337585 0.83
SCHEMBL5341906 0.83 SIGMAR1 (0.30) SIGMAR1
SCHEMBL886984 0.83 ALOX15 (0.33) SIGMAR1OPRM1OPRD1MEN1KMT2A
SCHEMBL886987 0.83 KMT2A (0.36) MEN1LMNAKMT2A
SCHEMBL27550619 0.82
SCHEMBL5341659 0.82 SLC18A3 (0.37) MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL5336900 0.82 BCHE (0.35) OPRM1OPRD1OPRK1MEN1LMNA
SCHEMBL27570117 0.82 CYP2D6 (0.33) OPRM1OPRK1MEN1LMNAKMT2A
SCHEMBL5340543 0.82 CYP3A4 (0.34) MEN1LMNAMAPK1KMT2ASMN1; SMN2
SCHEMBL14590798 0.81 BCHE (0.39) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7402639-B2 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators CIBA SPECIALTY CHEMICALS CORP. (US) 2008-07-22 US disclosed
US-7402639-B2 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators CIBA SPECIALTY CHEMICALS CORP. (US) 2008-07-22 US disclosed
US-7402639-B2 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators CIBA SPECIALTY CHEMICALS CORP. (US) 2008-07-22 US disclosed
US-6927295-B2 A polymerization catalyst for free radical polymerization of ethylenically unsaturated monomers CIBA SPECIALTY CHEMICALS CORP. (US) 2005-08-09 US disclosed
US-20050131177-A1 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (SE) 2005-06-16 US disclosed
US-6683142-B2 PROVIDE POLYMERIC RESIN PRODUCTS HAVING LOW POLYDISPERSITY. CIBA SPECIALTY CHEMICALS CORPORATION 2004-01-27 US disclosed
US-20030220423-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (CH) 2003-11-27 US disclosed
US-20020107397-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (CH) 2002-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050131177-A1 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators PYM1, PTGER1, CBR1 SIGMAR1 63/4885OPRM1 16/4885OPRD1 29/4885
US-20020107397-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators CBR1, PYM1, ELOC SIGMAR1 69/4885OPRM1 28/4885OPRD1 30/4885
US-20030220423-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators PYM1, ELOC, CBR1 SIGMAR1 88/4885OPRM1 35/4885OPRD1 43/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.