SCHEMBL886984

SCHEMBL886984

CCC1(C)CC(O)C(C)C(C)(CC)N1OC(C)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.33
MAPT P10636 1/20 0.32
OPRM1 P35372 2/20 0.31
OPRD1 P41143 2/20 0.31
UGCG Q16739 4/20 0.30
GBA2 Q9HCG7 4/20 0.30
GBA1 P04062 3/20 0.30
LCT P09848 3/20 0.30
MGAM O43451 2/20 0.30
SI P14410 2/20 0.30
SIGMAR1 Q99720 1/20 0.30
S1PR5 Q9H228 2/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
S1PR1 P21453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5341906 0.86 SIGMAR1 (0.30) SIGMAR1S1PR5S1PR1
SCHEMBL27550611 0.85 KCNH2 (0.33) S1PR5MEN1KMT2AS1PR1
SCHEMBL886987 0.83 KMT2A (0.36) MEN1KMT2A
SCHEMBL4803323 0.83 SIGMAR1 (0.31) OPRM1OPRD1SIGMAR1MEN1KMT2A
SCHEMBL27550619 0.83
SCHEMBL27570117 0.82 CYP2D6 (0.33) OPRM1S1PR5MEN1KMT2AS1PR1
SCHEMBL5336900 0.82 BCHE (0.35) OPRM1OPRD1S1PR5MEN1KMT2A
SCHEMBL5340543 0.82 CYP3A4 (0.34) MAPTS1PR5MEN1KMT2AS1PR1
SCHEMBL5337585 0.82
SCHEMBL14590798 0.82 BCHE (0.39) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10316114-B2 End-functionalized polymers BASF SE (DE) 2019-06-11 US disclosed
EP-2552971-B1 END-FUNCTIONALIZED POLYMERS BASF SE (DE) 2014-07-02 EP disclosed
US-8664324-B2 Pigment dispersants with modified copolymers BASF SE (DE) 2014-03-04 US disclosed
US-8664324-B2 Pigment dispersants with modified copolymers BASF SE (DE) 2014-03-04 US disclosed
US-8471031-B2 Process for the preparation of sterically hindered nitroxyl ethers BASF SE (DE) 2013-06-25 US disclosed
US-8471031-B2 Process for the preparation of sterically hindered nitroxyl ethers BASF SE (DE) 2013-06-25 US disclosed
US-20130030071-A1 END-FUNCTIONALIZED POLYMERS BASF SE (DE) 2013-01-31 US disclosed
US-20130030071-A1 END-FUNCTIONALIZED POLYMERS BASF SE (DE) 2013-01-31 US disclosed
EP-2247678-B1 FLUORO LEVELLING AGENTS BASF SE (DE) 2011-11-30 EP disclosed
WO-2011120947-A1 END-FUNCTIONALIZED POLYMERS BASF SE (DE) 2011-10-06 WO disclosed
EP-1436337-A1 PROCESS FOR THE PREPARATION OF HYDROXY-VINYL-AROMATIC POLYMERS OR COPOLYMERS BY ANIONIC OR CONTROLLED RADICAL POLYMERIZATION Ciba SC Holding AG (CH) 2004-07-14 EP disclosed
US-6683142-B2 PROVIDE POLYMERIC RESIN PRODUCTS HAVING LOW POLYDISPERSITY. CIBA SPECIALTY CHEMICALS CORPORATION 2004-01-27 US disclosed
US-20030220423-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (CH) 2003-11-27 US disclosed
US-6624306-B2 Stabilizer for addition polymer CIBA SPECIALTY CHEMICALS CORPORATION 2003-09-23 US disclosed
US-20030166939-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides NESVADBA PETER (CH) 2003-09-04 US disclosed
US-6583245-B1 Ethylenically unsaturated compound (acrylate or acrylamide) having sterically hindered amine, hydroxyphenyl triazine, hydroxyphenylbenzotriazole or a o-hydroxy-benzophenone group; a nitroxyl free radical initiator CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-24 US disclosed
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. 2003-04-03 US disclosed
WO-2003022895-A1 PROCESS FOR THE PREPARATION OF HYDROXY-VINYL-AROMATIC POLYMERS OR COPOLYMERS BY ANIONIC OR CONTROLLED RADICAL POLYMERIZATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-03-20 WO disclosed
US-20020107397-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (CH) 2002-08-08 US disclosed
US-6353107-B1 FREE RADICAL CATALYSTS FOR ADDITION POLYMERIZATION; NARROW MOLECULAR WEIGHT DISTRIBUTION; HIGH PURITY AND COLORLESS CIBA SPECIALTY CHEMICALS CORPORATION 2002-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166939-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 ALOX15 125/4885MAPT 3356/4885OPRM1 18/4885
US-20020107397-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators CBR1, PYM1, ELOC ALOX15 112/4885MAPT 4391/4885OPRM1 28/4885
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 ALOX15 125/4885MAPT 3356/4885OPRM1 18/4885
US-20030220423-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators PYM1, ELOC, CBR1 ALOX15 114/4885MAPT 4497/4885OPRM1 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.