Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728201 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HPGDCASP1MPI | |
| SCHEMBL1137933 | 0.77 | TTR (0.55) | ALDH1A1SMN1; SMN2HPGDCASP1ANPEP | |
| SCHEMBL12235610 | 0.74 | ANPEP (0.58) | ALDH1A1SMN1; SMN2HPGDCASP1MPI | |
| SCHEMBL12235614 | 0.71 | CYP1B1 (0.42) | ALDH1A1ANPEPDPP4MAOAMAPT | |
| SCHEMBL29649695 | 0.71 | CES1 (0.71) | ALDH1A1PARK7MAOAHSD17B10MAOB | |
| SCHEMBL5114051 | 0.71 | CES1 (0.71) | ALDH1A1PARK7MAOAHSD17B10MAOB | |
| SCHEMBL31528039 | 0.69 | PARK7 (0.45) | ALDH1A1SMN1; SMN2HPGDCASP1MPI | |
| SCHEMBL11250926 | 0.67 | ATAD2 (0.44) | ALDH1A1SMN1; SMN2HPGDCASP1MPI | |
| SCHEMBL31528258 | 0.67 | PARK7 (0.50) | ALDH1A1SMN1; SMN2HPGDCASP1MPI | |
| SCHEMBL9394398 | 0.66 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2HPGDMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7374583-B2 | Cationic azacyanine dyes and coloring agents containing said dyes | THE PROCTER & GAMBLE COMPANY (US) | 2008-05-20 | — | — | US | disclosed |
| US-20070220685-A1 | Cationic azacyanine dyes and coloring agents containing said dyes | THE PROCTER & GAMBLE COMPANY (US) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070220685-A1 | Cationic azacyanine dyes and coloring agents containing said dyes | KRT18, DNMT1, NUP205 | ALDH1A1 1945/4885SMN1; SMN2 2790/4885HPGD 2020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.