Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 3/20 | 0.47 |
| ▸ | GLS | O94925 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3157695 | 0.96 | XIAP (0.49) | XIAPGLSPOLBALDH1A1CCNA2 | |
| SCHEMBL4804382 | 0.87 | XIAP (0.45) | XIAPGLSPOLBALDH1A1CCNA2 | |
| SCHEMBL4801228 | 0.83 | XIAP (0.45) | XIAPGLSPOLBALDH1A1ADRB3 | |
| SCHEMBL3162800 | 0.81 | XIAP (0.45) | XIAPGLSPOLBALDH1A1CCNA2 | |
| SCHEMBL3172004 | 0.81 | XIAP (0.43) | XIAPGLSPOLBALDH1A1CCNA2 | |
| SCHEMBL4803743 | 0.81 | XIAP (0.46) | XIAPGLSPOLBALDH1A1ADRB3 | |
| SCHEMBL13452506 | 0.80 | XIAP (0.49) | XIAPGLSCCNA2CDK2CCNA1 | |
| Formic Acid SCHEMBL3598996 | 0.78 | XIAP (0.36) | XIAPADRB3 | |
| SCHEMBL4798134 | 0.77 | ACKR3 (0.46) | XIAPGLSPOLBALDH1A1ADRB3 | |
| SCHEMBL5767301 | 0.76 | MEN1 (0.41) | XIAPGLSPOLBALDH1A1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348347-B2 | Substituted 4,5,6,7-tetrahydrobenzthiazol-2-ylamine compounds | GRUENENTHAL GMBH (DE) | 2008-03-25 | — | — | US | disclosed |
| US-20070027315-A1 | Substituted 4,5,6,7-tetrahydrobenzthiazol-2-ylamine compounds | GRUENENTHAL GMBH (DE) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027315-A1 | Substituted 4,5,6,7-tetrahydrobenzthiazol-2-ylamine compounds | TPH2, HTR6, TPH1 | XIAP 3750/4885GLS 705/4885POLB 3518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.