Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4674536 | 0.88 | PTGDR2 (0.35) | CACNA1GCACNA1HCHRM2CHRM1CHRM3 | |
| SCHEMBL4681956 | 0.85 | OPRL1 (0.48) | CACNA1GCACNA1HC5AR1OPRL1OPRM1 | |
| SCHEMBL4804451 | 0.84 | CACNA1G (0.43) | CYP3A4CACNA1GCACNA1HC5AR1OPRL1 | |
| SCHEMBL3803735 | 0.84 | OPRM1 (0.49) | HSD11B1CHRM2CHRM1CHRM3OPRL1 | |
| SCHEMBL4676160 | 0.84 | HSD11B1 (0.45) | HSD11B1TNKSPARP1PARP2CHRM1 | |
| SCHEMBL4675602 | 0.82 | CYP3A4 (0.41) | CYP3A4HSD11B1TNKSPARP1PARP2 | |
| SCHEMBL4796827 | 0.82 | POLB (0.40) | CYP3A4CHRM2CHRM1CHRM3 | |
| SCHEMBL4678001 | 0.79 | FPR2 (0.42) | OPRM1OPRK1 | |
| SCHEMBL4682261 | 0.79 | DRD2 (0.44) | CHRM2CHRM1CHRM3OPRL1OPRM1 | |
| SCHEMBL4674480 | 0.79 | ALDH1A1 (0.44) | CYP3A4TNKSPARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |