Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 5/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4804708 | 0.88 | PBRM1 (0.56) | ACLYCA1CA2CA9ATM | |
| SCHEMBL4190433 | 0.81 | ACLY (0.50) | ACLYKAT6A | |
| SCHEMBL28471630 | 0.80 | PTK2B (0.50) | ACLYCA1CA2CA9ATM | |
| SCHEMBL4804704 | 0.76 | ITGA1 (0.60) | ACLYCA1CA2KAT6AHSD17B1 | |
| SCHEMBL3105323 | 0.75 | TDP1 (0.78) | CA1CA2ATMTDP1L3MBTL1 | |
| SCHEMBL14547178 | 0.73 | PTK2B (0.44) | ACLYATMTDP1L3MBTL1HSD17B1 | |
| SCHEMBL29941476 | 0.73 | DHODH (0.68) | TDP1L3MBTL1DHODHADAMTS4ERN1 | |
| SCHEMBL4553485 | 0.73 | TET2 (0.41) | ACLYKAT6AHSD17B1HSD17B2 | |
| SCHEMBL250118 | 0.72 | PTK2B (0.45) | ACLYHSD17B1HSD17B2 | |
| SCHEMBL5605746 | 0.72 | TET2 (0.40) | ACLYKAT6AHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924554-A1 | SULPHONAMIDE DERIVATIVES | Biotie Therapies Corp. (FI) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007034035-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2007-03-29 | — | — | WO | disclosed |