Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 17/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553485 | 0.90 | TET2 (0.41) | ACLYPTPN1KAT6A | |
| SCHEMBL5605746 | 0.88 | TET2 (0.40) | ACLYPTPN1KAT6A | |
| SCHEMBL5277265 | 0.85 | PTGS2 (0.39) | ACLYPTPN1KAT6A | |
| SCHEMBL16341242 | 0.85 | PKM (0.41) | ACLYPTPN1KAT6A | |
| Sulfur Dioxide SCHEMBL28794204 | 0.83 | TET2 (0.37) | ACLYPTPN1KAT6A | |
| Sulfur Dioxide SCHEMBL29103741 | 0.83 | TET2 (0.37) | ACLYPTPN1KAT6A | |
| Biphenyl SCHEMBL19280397 | 0.82 | KAT6A (0.48) | ACLYPTPN1KAT6A | |
| Sulfur Dioxide SCHEMBL28538525 | 0.82 | PTGS2 (0.37) | ACLYPTPN1 | |
| SCHEMBL21999649 | 0.81 | ACLY (0.47) | ACLYKAT6A | |
| SCHEMBL4804700 | 0.81 | ACLY (0.55) | ACLYKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101300271-A | Collagen receptor I-domain binding modulators | BIOTIE THERAPIES CORP (FI) | 2008-11-05 | — | — | CN | claimed |
| CN-101268041-A | Sulphonamide derivatives | BIOTIE THERAPIES CORP (FI) | 2008-09-17 | — | — | CN | claimed |
| US-20090023735-A1 | Sulphonamide Derivatives | BIOTIE THERAPIES CORP. (FI) | 2009-01-22 | — | — | US | disclosed |
| CN-101300271-A | Collagen receptor I-domain binding modulators | BIOTIE THERAPIES CORP (FI) | 2008-11-05 | — | — | CN | disclosed |
| CN-101268041-A | Sulphonamide derivatives | BIOTIE THERAPIES CORP (FI) | 2008-09-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023735-A1 | Sulphonamide Derivatives | HCAR1, ADGRE5, ALK | ACLY 3672/4885PTPN1 342/4885KAT6A 1293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.