Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369033 | 0.80 | KMT2A (0.45) | TSHRKMT2ACYP2D6LMNANR1I2 | |
| SCHEMBL3363020 | 0.78 | POLB (0.41) | TSHRKMT2ACYP2D6LMNACYP3A4 | |
| SCHEMBL3367006 | 0.77 | KMT2A (0.48) | TSHRKMT2ACYP2D6LMNACYP3A4 | |
| SCHEMBL13412662 | 0.72 | TSHR (0.48) | TSHRKMT2ACYP2D6LMNANR1I2 | |
| SCHEMBL19937304 | 0.70 | KMT2A (0.61) | TSHRKMT2ACYP2D6LMNANR1I2 | |
| SCHEMBL13474844 | 0.70 | KMT2A (0.61) | TSHRKMT2ACYP2D6LMNANR1I2 | |
| SCHEMBL6813656 | 0.70 | TSHR (0.68) | TSHRKMT2ACYP2D6LMNAALDH1A1 | |
| SCHEMBL9550733 | 0.70 | TSHR (0.48) | TSHRKMT2ACYP2D6LMNACYP3A4 | |
| SCHEMBL1138712 | 0.69 | TSHR (0.74) | TSHRKMT2ALMNAALDH1A1HSD17B10 | |
| SCHEMBL1138561 | 0.69 | TSHR (0.44) | TSHRKMT2AALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402675-B2 | Process for the synthesis of amine ethers from secondary amino oxides | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-07-22 | — | — | US | disclosed |
| US-6900328-B2 | Process for the synthesis of amine ethers from secondary amino oxides | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-05-31 | — | — | US | disclosed |
| US-20050043552-A1 | Process for the synthesis of amine ethers from secondary amino oxides | HAFNER ANDREAS (CH) | 2005-02-24 | — | — | US | disclosed |
| US-20030171461-A1 | Process for the synthesis of amine ethers from secondary amino oxides | CIBA SPECIALTY CHEMICALS CORP. | 2003-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043552-A1 | Process for the synthesis of amine ethers from secondary amino oxides | CYC1, AOC2, CBR1 | TSHR 831/4885KMT2A 1447/4885CYP2D6 72/4885 |
| US-20030171461-A1 | Process for the synthesis of amine ethers from secondary amino oxides | IL4I1, HCCS, CBR1 | TSHR 1905/4885KMT2A 1055/4885CYP2D6 983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.