Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 7/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 3/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18670789 | 0.90 | STAT3 (0.32) | STAT3STAT1SMPD3 | |
| SCHEMBL27633442 | 0.83 | MAPT (0.36) | STAT3STAT1SMPD3KDM4EALDH1A1 | |
| Methoxymethane SCHEMBL27581743 | 0.82 | STAT3 (0.38) | STAT3STAT1 | |
| SCHEMBL3276862 | 0.81 | ALDH1A1 (0.43) | STAT3STAT1AMY1AKDM4EALDH1A1 | |
| SCHEMBL7738113 | 0.80 | STAT3 (0.41) | STAT3STAT1 | |
| SCHEMBL7738107 | 0.80 | STAT3 (0.41) | STAT3STAT1 | |
| SCHEMBL164026 | 0.80 | STAT3 (0.41) | STAT3STAT1 | |
| SCHEMBL27689652 | 0.80 | STAT3 (0.35) | STAT3STAT1 | |
| SCHEMBL6479855 | 0.78 | STAT3 (0.49) | STAT3STAT1 | |
| SCHEMBL9866324 | 0.78 | STAT3 (0.49) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051288-B | Industrial process for monoalkylating piperidine nitrogen in piperidine derivatives with deuterated alkyl groups | 大塚制药株式会社 | 2023-08-25 | — | — | CN | disclosed |
| EP-1718201-B1 | SUBSTITUTED PORPHYRINS | UNIV DUKE (US) | 2016-09-14 | — | — | EP | disclosed |
| US-20150344509-A1 | SUBSTITUTED PORPHYRINS | UNIV DUKE (US) | 2015-12-03 | — | — | US | disclosed |
| US-9096628-B2 | Substituted porphyrins | DUKE UNIVERSITY (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140080797-A1 | SUBSTITUTED PORPHYRINS | DUKE UNIVERSITY (US) | 2014-03-20 | — | — | US | disclosed |
| US-8618089-B2 | Substituted porphyrins | DUKE UNIVERSITY (US) | 2013-12-31 | — | — | US | disclosed |
| US-20120264725-A1 | SUBSTITUTED PORPHYRINS | BATINIC-HABERLE INES (US) | 2012-10-18 | — | — | US | disclosed |
| US-8183364-B2 | Substituted porphyrins | DUKE UNIVERSITY (US) | 2012-05-22 | — | — | US | disclosed |
| EP-1274983-B1 | COLORIMETRIC ARTIFICIAL NOSE HAVING AN ARRAY OF DYES AND METHOD FOR ARTIFICIAL OLFACTION | UNIV ILLINOIS (US) | 2012-02-01 | — | — | EP | disclosed |
| US-20100305083-A1 | SUBSTITUTED PORPHYRINS | BATINIC-HABERLE INES | 2010-12-02 | — | — | US | disclosed |
| US-7807825-B2 | Substituted porphyrins | DUKE UNIVERSITY (US) | 2010-10-05 | — | — | US | disclosed |
| US-20080021007-A1 | Substituted Porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-01-24 | — | — | US | disclosed |
| US-7261857-B2 | Colorimetric artificial nose having an array of dyes and method for artificial olfaction | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-08-28 | — | — | US | disclosed |
| EP-1718201-A1 | SUBSTITUTED PORPHYRINS | Duke University (US) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005077269-A1 | SUBSTITUTED PORPHYRINS | DUKE UNIVERSITY (US) | 2005-08-25 | — | — | WO | disclosed |
| US-20030166298-A1 | Colorimetric artificial nose having an array of dyes and method for artificial olfaction | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2003-09-04 | — | — | US | disclosed |
| US-20030143112-A1 | Colorimetric artificial nose having an array of dyes and method for artificial olfaction | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2003-07-31 | — | — | US | disclosed |
| US-20030129085-A1 | Siloxy porpyhrins and metal complexes thereof | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2003-07-10 | — | — | US | disclosed |
| US-6495102-B1 | Colorimetric artificial nose having an array of dyes and method of artificial olfaction | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2002-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344509-A1 | SUBSTITUTED PORPHYRINS | PPOX, FECH, MB | STAT3 546/4885STAT1 729/4885AMY1A 1486/4885 |
| US-20120264725-A1 | SUBSTITUTED PORPHYRINS | PPOX, FECH, MB | STAT3 546/4885STAT1 729/4885AMY1A 1486/4885 |
| US-20080021007-A1 | Substituted Porphyrins | SOD3, SOD1, PRDX3 | STAT3 4525/4885STAT1 4424/4885AMY1A 1527/4885 |
| US-20140080797-A1 | SUBSTITUTED PORPHYRINS | PPOX, FECH, MB | STAT3 546/4885STAT1 729/4885AMY1A 1486/4885 |
| US-20100305083-A1 | SUBSTITUTED PORPHYRINS | SOD3, SOD1, PRDX3 | STAT3 4527/4885STAT1 4415/4885AMY1A 1202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.