SCHEMBL4805327

SCHEMBL4805327

CC(C)(c1c(O)c(Cl)c(Cl)c(Cl)c1Cl)c1c(O)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
HPGD P15428 3/20 0.47
HSD17B10 Q99714 3/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP1A2 P05177 4/20 0.43
CYP2C9 P11712 4/20 0.43
HIF1A Q16665 3/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.33
MAPK1 P28482 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112121 0.86 TSHR (0.50) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL28030118 0.75 HSD17B10 (0.83) TSHRHPGDHSD17B10MEN1ALDH1A1
SCHEMBL11789672 0.74 TSHR (0.50) TSHRHPGDHSD17B10MEN1ALDH1A1
SCHEMBL23079376 0.72 HPGD (0.40) TSHRHPGDHSD17B10MEN1ALDH1A1
SCHEMBL5587548 0.71 ALDH1A1 (0.37) TSHRHPGDHSD17B10MEN1ALDH1A1
SCHEMBL298363 0.70 MEN1 (0.32) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL1330735 0.67 HSD17B10 (1.00) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL1492 0.67 HSD17B10 (1.00) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL23121452 0.67 HSD17B10 (1.00) TSHRHPGDHSD17B10MEN1ALDH1A1
Perchlorobenzene SCHEMBL28269084 0.67 HSD17B10 (1.00) TSHRHPGDHSD17B10MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200205560-A1 POROUS POLYMERIC POLISHING BRISTLES AND METHODS FOR THEIR MANUFACTURE JH RHODES COMPANY, INC. 2020-07-02 US disclosed
US-9440326-B2 Non-planar glass polishing pad and method of manufacture JH RHODES COMPANY, INC. (US) 2016-09-13 US disclosed
US-9050697-B2 Self-conditioning polishing pad and a method of making the same JH RHODES COMPANY, INC. (US) 2015-06-09 US disclosed
US-20140024296-A1 NON-PLANAR GLASS POLISHING PAD AND METHOD OF MANUFACTURE JH RHODES COMPANY, INC. 2014-01-23 US disclosed
US-20130252519-A1 SELF-CONDITIONING POLISHING PAD AND A METHOD OF MAKING THE SAME JH RHODES COMPANY, INC. (US) 2013-09-26 US disclosed
US-20080146129-A1 Fast break-in polishing pad and a method of making the same KOUZUMA MAKOTO 2008-06-19 US disclosed