Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4805327 | 0.86 | TSHR (0.47) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| SCHEMBL5608008 | 0.84 | HIF1A (0.36) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| SCHEMBL298363 | 0.78 | MEN1 (0.32) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| SCHEMBL25881 | 0.78 | ESR1 (0.58) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| Pentachlorophenol SCHEMBL28030118 | 0.77 | HSD17B10 (0.83) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| SCHEMBL23079376 | 0.74 | HPGD (0.40) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| Tetrachlorohydroquinone SCHEMBL48198 | 0.73 | HSD17B10 (0.90) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| SCHEMBL5587548 | 0.73 | ALDH1A1 (0.37) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| SCHEMBL1686572 | 0.73 | TSHR (0.53) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| SCHEMBL10943632 | 0.71 | TSHR (0.60) | TSHRHPGDHSD17B10MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 594 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763560-A1 | POLYARYLATE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 2007-03-21 | — | — | EP | claimed |
| US-7109274-B2 | Polyarylate compositions | GENERAL ELECTRIC COMPANY (US) | 2006-09-19 | — | — | US | claimed |
| WO-2006012161-A1 | POLYARYLATE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 2006-02-02 | — | — | WO | claimed |
| US-20060004152-A1 | Polyarylate compositions | GENERAL ELECTRIC COMPANY | 2006-01-05 | — | — | US | claimed |
| EP-1560871-A1 | METHOD FOR MAKING COPOLYCARBONATES | GENERAL ELECTRIC COMPANY (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004041907-A1 | METHOD FOR MAKING COPOLYCARBONATES | GENERAL ELECTRIC COMPANY (US) | 2004-05-21 | — | — | WO | claimed |
| US-6657038-B1 | Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt | GENERAL ELECTRIC COMPANY | 2003-12-02 | — | — | US | claimed |
| US-6576739-B2 | Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups | GENERAL ELECTRIC COMPANY | 2003-06-10 | — | — | US | claimed |
| US-20020111456-A1 | Method of polycarbonate preparation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2002-08-15 | — | — | US | claimed |
| WO-2001085825-A2 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2001-11-15 | — | — | WO | claimed |
| US-12570870-B2 | Curable compositions, abrasion-resistant articles, and method of thermoforming the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-03-10 | — | — | US | disclosed |
| US-12173178-B2 | Polyfunctional hydrazide crosslinker | PPG INDUSTRIES OHIO, INC. (US) | 2024-12-24 | — | — | US | disclosed |
| CN-113166500-B | Additive-containing polyethylene for increasing environmental stress cracking resistance | SABIC环球技术有限责任公司 | 2024-11-08 | — | — | CN | disclosed |
| US-20240117215-A1 | POLYFUNCTIONAL HYDRAZIDE CROSSLINKER | PPG INDUSTRIES OHIO, INC. (US) | 2024-04-11 | — | — | US | disclosed |
| US-11898025-B2 | Polyethylene with additives for increased environmental stress crack resistance | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2024-02-13 | — | — | US | disclosed |
| EP-0029242-A2 | Process for producing a mixed halogen-containing polycarbonate resin | MITSUBISHI KASEI CORPORATION (JP) | 1981-05-27 | — | — | EP | disclosed |
| US-4212781-A | BLEND OF EPOXY RESIN, CARBOXY-FUNCTIONAL ADDITION POLYMER AND GRAFT POLYMER OF THE TWO | SCM CORPORATION (US) | 1980-07-15 | — | — | US | disclosed |
| US-4020306-A | High voltage switching device with calcium-aluminum glass filled resin insulator support | ZAHNER HANSRUEDI | 1977-04-26 | — | — | US | disclosed |
| US-3957905-A | HALOGENATED BISPHENYL COMPOUND, ANTIMONY COMPOUND | TOYO BOSEKI KABUSHIKI KAISHA (JA) | 1976-05-18 | — | — | US | disclosed |
| US-3936400-A | Flame retardant foamed polyester compositions | GENERAL ELECTRIC COMPANY (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570870-B2 | Curable compositions, abrasion-resistant articles, and method of thermoforming the same | VCL, LBR, ACR | TSHR 927/4885HPGD 4454/4885HSD17B10 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.