Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28749742 | 0.79 | HTR4 (0.65) | GAACYP3A4HTR4GLAMEN1 | |
| SCHEMBL4733762 | 0.78 | MAPT (0.49) | MEN1ALDH1A1KMT2A | |
| SCHEMBL384749 | 0.78 | GAA (1.00) | GAACYP3A4HTR4GLAALDH1A1 | |
| Hydrochloric Acid SCHEMBL7405359 | 0.77 | GAA (0.97) | GAACYP3A4HTR4GLAALDH1A1 | |
| SCHEMBL8292456 | 0.77 | GAA (0.79) | GAACYP3A4HTR4GLAMEN1 | |
| SCHEMBL9379986 | 0.75 | GAA (0.74) | GAACYP3A4HTR4GLAMEN1 | |
| SCHEMBL7280230 | 0.74 | GAA (0.73) | GAACYP3A4HTR4GLAALDH1A1 | |
| SCHEMBL7351910 | 0.74 | GAA (0.73) | GAACYP3A4HTR4GLAALDH1A1 | |
| SCHEMBL725809 | 0.74 | GAA (0.73) | GAACYP3A4HTR4GLAALDH1A1 | |
| SCHEMBL99019 | 0.74 | GAA (0.73) | GAACYP3A4HTR4GLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427260-B2 | Efficient methods for solid phase synthesis using trityl chloride resins | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2008-09-23 | — | — | US | disclosed |
| US-20040096904-A1 | Efficient methods for solid phase synthesis using trityl chloride resins | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2004-05-20 | — | — | US | disclosed |
| WO-2002079278-A1 | EFFICIENT METHODS FOR SOLID PHASE SYNTHESIS USING TRITYL CHLORIDE RESINS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2002-10-10 | — | — | WO | disclosed |