Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL4806415

N[C@@H](Cc1ccco1)C(=O)O.O=C(O)C(F)(F)F

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GRB2 P62993 1/20 0.50
SLC7A5 Q01650 2/20 0.49
PKM P14618 2/20 0.49
PTGS1 P23219 2/20 0.49
ALPI P09923 1/20 0.49
XIAP P98170 1/20 0.49
PTPN1 P18031 2/20 0.47
SLC1A3 P43003 2/20 0.47
SLC1A2 P43004 2/20 0.47
SLC1A1 P43005 2/20 0.47
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
ALOX5 P09917 1/20 0.43
MLYCD O95822 1/20 0.42
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39
GAA P10253 1/20 0.39
PTGS2 P35354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL180118 0.91 SLC1A3 (0.54) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL1663153 0.91 SLC1A3 (0.54) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL599915 0.91 SLC1A3 (0.54) SLC7A5PKMPTGS1ALPIXIAP
Trifluoroacetic Acid SCHEMBL7415089 0.79 MLYCD (0.47) SLC1A3SLC1A2SLC1A1NPC1RAB9A
D-Glutamate SCHEMBL29008193 0.78 SLC1A3 (0.50) SLC7A5PKMPTGS1ALPIXIAP
Dl-Phenylalanine SCHEMBL7450242 0.77 SLC7A5 (0.81) GRB2SLC7A5PKMPTGS1ALPI
Dl-Phenylalanine SCHEMBL16649156 0.77 SLC7A5 (0.81) GRB2SLC7A5PKMPTGS1ALPI
Phenylalanine SCHEMBL3047281 0.77 SLC7A5 (0.81) GRB2SLC7A5PKMPTGS1ALPI
SCHEMBL10305129 0.77 ALOX5 (0.54) SLC1A3SLC1A2SLC1A1NPC1RAB9A
SCHEMBL6248378 0.77 ALOX5 (0.54) SLC1A3SLC1A2SLC1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7335516-B2 Methods to improve immunogenicity of antigens and specificity of antibodies SEREX, INC. (US) 2008-02-26 US disclosed
US-7303750-B2 Methods to improve immunogenicity of antigens and specificity of antibodies SEREX, INC. (US) 2007-12-04 US disclosed
US-7147858-B2 Methods to improve immunogenicity of antigens and specificity of antibodies SEREX, INC. (US) 2006-12-12 US disclosed
US-20030113339-A1 Methods to improve immunogenicity of antigens and specificity of antibodies SEREX, INC. 2003-06-19 US disclosed
US-20030095976-A1 Immunizing with the hapten linked to a carrier protein and boosting the immunization with the hapten conjugated to the carrier by a different linker, especially a 2-amino-3-furylpropionyl linkage SEREX, INC. 2003-05-22 US disclosed
US-20030086939-A1 Methods to improve immunogenicity of antigens and specificity of antibodies SEREX, INC. 2003-05-08 US disclosed
US-20030077287-A1 Methods to improve immunogenicity of antigens and specificity of antibodies SEREX, INC. 2003-04-24 US disclosed
US-6455047-B1 IMPROVING SPECIFIC IMMUNE RESPONSES TO SMALL IMMUNOGENS, HAPTENS, HAS BEEN DEVELOPED BY CHANGING THE LINKAGE BETWEEN THE HAPTEN AND CARRIER BEING USED FOR IMMUNIZATION. HIGH AFFINITY ANTIBODIES TO THE HAPTEN COTININE HAVE BEEN PRODUCED SEREX, INC. 2002-09-24 US disclosed
EP-1015028-A2 METHODS TO IMPROVE IMMUNOGENICITY OF ANTIGENS AND SPECIFICITY OF ANTIBODIES SEREX, INC. (US) 2000-07-05 EP disclosed
WO-1999013907-A9 METHODS TO IMPROVE IMMUNOGENICITY OF ANTIGENS AND SPECIFICITY OF ANTIBODIES SEREX INC (US) 1999-09-10 WO disclosed
WO-1999013907-A2 METHODS TO IMPROVE IMMUNOGENICITY OF ANTIGENS AND SPECIFICITY OF ANTIBODIES SEREX, INC. (US) 1999-03-25 WO disclosed