Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25954205 | 0.93 | SLC2A1 (0.59) | SLC2A1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1409015 | 0.93 | SLC2A1 (0.59) | SLC2A1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL15763654 | 0.86 | ALDH1A1 (0.54) | SLC2A1ALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL26808251 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ATSHRTDP1 | |
| SCHEMBL362964 | 0.82 | TSHR (0.43) | ALDH1A1MEN1KMT2ATSHRALOX15 | |
| SCHEMBL1793818 | 0.81 | NR1H2 (0.48) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL6491080 | 0.81 | SLC2A1 (0.49) | SLC2A1ALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL30056216 | 0.79 | LMNA (0.41) | ALDH1A1RAB9ANPC1TSHRTDP1 | |
| SCHEMBL4796677 | 0.79 | MEN1 (0.44) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL13766167 | 0.79 | ESR1 (0.41) | SLC2A1ALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444860-B1 | — | — | None | — | — | US | disclosed |
| US-9487693-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2016-11-08 | — | — | US | disclosed |
| US-9487693-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2016-11-08 | — | — | US | disclosed |
| US-20140154527-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| US-20140154527-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| US-8709308-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2014-04-29 | — | — | US | disclosed |
| US-8709308-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2014-04-29 | — | — | US | disclosed |
| US-20140034884-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2014-02-06 | — | — | US | disclosed |
| US-20140034884-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2014-02-06 | — | — | US | disclosed |
| US-20140030529-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |
| WO-2000049010-A1 | NAPHTHOPYRANS AND PHENANTHROPYRANS ANNELATED IN C5-C6 WITH A BICYCLIC GROUP, AND COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THEM | CORNING S.A. (FR) | 2000-08-24 | — | — | WO | disclosed |
| EP-1000025-A1 | SUBSTITUTED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0628064-B1 | PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 1999-04-07 | — | — | EP | disclosed |
| WO-1998055457-A1 | SUBSTITUTED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 1998-12-10 | — | — | WO | disclosed |
| US-5658500-A | REVERSIBLE PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 1997-08-19 | — | — | US | disclosed |
| US-5585042-A | REVERSIBLE CHANGE IN COLOR WHEN EXPOSURED TO ULTRAVIOLET RADIATION | TRANSITIONS OPTICAL, INC. (US) | 1996-12-17 | — | — | US | disclosed |
| EP-0628064-A1 | PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 1994-12-14 | — | — | EP | disclosed |
| US-5369158-A | And polymer | TRANSITIONS OPTICAL, INC. (US) | 1994-11-29 | — | — | US | disclosed |
| WO-1993017071-A1 | PHOTOCHROMIC NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1993-09-02 | — | — | WO | disclosed |
| US-5238981-A | PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 1993-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140030529-A1 | CHROMENE COMPOUND | TST, CNOT1, CNOT9 | SLC2A1 3449/4885ALDH1A1 1884/4885RAB9A 2258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.