SCHEMBL4806744

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4798966	0.78	CYP11B1 (0.53)	CYP11B1CYP11B2HPGDPTGS2CYP1A2
	SCHEMBL4796428	0.78	CYP11B2 (0.53)	CYP11B1CYP11B2HPGDPTGS2SIGMAR1
	SCHEMBL10993362	0.76	PTGS2 (0.64)	CYP11B1CYP11B2HPGDPTGS2CYP1A2
	SCHEMBL27915572	0.72	PTGS2 (0.55)	CYP11B1CYP11B2HPGDPTGS2CYP1A2
	SCHEMBL27934319	0.70	PTGS2 (0.55)	CYP11B1CYP11B2HPGDPTGS2CYP1A2
	SCHEMBL27915575	0.70	PTGS2 (0.52)	CYP11B1CYP11B2HPGDPTGS2L3MBTL1
	SCHEMBL1950743	0.69	CYP11B1 (1.00)	CYP11B1CYP11B2SIGMAR1
	SCHEMBL20232995	0.69	L3MBTL1 (0.60)	CYP11B1CYP11B2HPGDCYP1A2CYP2C19
	SCHEMBL27915593	0.69	PDE10A (0.52)	CYP11B1CYP11B2HPGDPTGS2CYP1A2
	SCHEMBL12771538	0.69	HTT (0.72)	CYP11B1CYP11B2HPGDNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.