SCHEMBL4806940

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5411461	0.87	APOBEC3G (0.40)	LMNAGAAALDH1A1CYP2C9POLB
	SCHEMBL4806464	0.85	CYP3A4 (0.43)	LMNAGAAALDH1A1GABRPGABRD
	SCHEMBL4809687	0.83	NCOA1 (0.39)	LMNAGAAALDH1A1GABRPGABRD
	SCHEMBL4811037	0.77	GABRP (0.46)	LMNAGAAALDH1A1GABRPGABRD
	SCHEMBL4799252	0.76	APOBEC3G (0.45)	LMNAGAAALDH1A1POLBMPI
	SCHEMBL5377126	0.75	CYP3A4 (0.40)	CYP2C9SLC6A2SLC6A4SLC6A3CYP3A4
	SCHEMBL3521491	0.75	TDP1 (0.56)	LMNAALDH1A1TDP1APOBEC3GSMN1; SMN2
	SCHEMBL5374337	0.73	CYP3A4 (0.47)	CYP2C9SLC6A2SLC6A4SLC6A3FNTA
	SCHEMBL5368768	0.73	CYP3A4 (0.42)	CYP2C9SLC6A2SLC6A4SLC6A3CYP3A4
	SCHEMBL4805650	0.73	CYP3A4 (0.47)	LMNAGAAALDH1A1GABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.