SCHEMBL4806969

SCHEMBL4806969

CC(=O)c1nc2cccc(N)c2[nH]1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 3/20 0.36
PTPN11 Q06124 2/20 0.36
HRH4 Q9H3N8 2/20 0.36
CHEK1 O14757 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
GFER P55789 1/20 0.35
BRD4 O60885 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PARP1 P09874 2/20 0.34
LMNA P02545 2/20 0.34
XDH P47989 2/20 0.33
HTT P42858 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
KCNH2 Q12809 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6961429 0.85 PIN1 (0.41) MAPTPTPN11NPC1RAB9AHPGD
SCHEMBL3726215 0.85 IKBKB (0.37) HSD17B10MAPTPTPN11HRH4CHEK1
SCHEMBL55693 0.83 ALDH1A1 (0.44) HSD17B10MAPTPTPN11CHEK1NPC1
SCHEMBL30831141 0.81 BRPF1 (0.42) HSD17B10TP53MAPTNPC1RAB9A
SCHEMBL28882676 0.81 BRPF1 (0.42) HSD17B10TP53MAPTNPC1RAB9A
SCHEMBL6952309 0.78 CDK9 (0.48) MAPTHRH4NPC1RAB9AHPGD
SCHEMBL10823966 0.73 ALDH1A1 (0.51) HSD17B10TP53MAPTCHEK1HPGD
SCHEMBL1013611 0.73 PARP1 (0.46) HSD17B10MAPTNPC1RAB9AHPGD
SCHEMBL28309524 0.73 ALDH1A1 (0.37) HSD17B10MAPTNPC1RAB9AHPGD
SCHEMBL3938947 0.72 TDP1 (0.40) HSD17B10MAPTCHEK1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2977417-B1 HYDROPHILIC SURFACE TREATMENT AGENT FOR ALUMINUM-CONTAINING METAL HEAT EXCHANGERS HAVING EXCELLENT DRAINAGE NIHON PARKERIZING (JP) 2017-08-02 EP disclosed
US-9534132-B2 Hydrophilic surface treatment agent for aluminum-containing metal heat exchangers having excellent drainage NIHON PARKERIZING CO., LTD. (JP) 2017-01-03 US disclosed
EP-2977417-A1 HYDROPHILIC SURFACE TREATMENT AGENT FOR ALUMINUM-CONTAINING METAL HEAT EXCHANGERS HAVING EXCELLENT DRAINAGE Nihon Parkerizing Co., Ltd. (JP) 2016-01-27 EP disclosed
US-20150232681-A1 HYDROPHILIC SURFACE TREATMENT AGENT FOR ALUMINUM-CONTAINING METAL HEAT EXCHANGERS HAVING EXCELLENT DRAINAGE NIHON PARKERIZING CO., LTD. (JP) 2015-08-20 US disclosed
US-7432312-B2 Polyurethane foam having deodorization property or antibacterial effect TAKASHIMA CO., LTD (JAPAN CORP) (JP) 2008-10-07 US disclosed
US-20050245627-A1 Polyurethane foam having deodorization property or antibacterial effect TAKASHIMA CO., LTD. (JAPAN CORPORATION) (JP) 2005-11-03 US disclosed
EP-1136591-A1 HYDROPHILIZING AGENT FOR METALLIC MATERIAL, HYDROPHILIZING FLUID, METHOD OF HYDROPHILIZING, METALLIC MATERIAL, AND HEAT EXCHANGER NIHON PARKERIZING CO., LTD. (JP) 2001-09-26 EP disclosed