Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232191 | 0.74 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1GLANOTUM | |
| SCHEMBL22526968 | 0.74 | HTR2C (0.50) | ALDH1A1MAPK1L3MBTL1HTR2CGLA | |
| SCHEMBL7060349 | 0.74 | ITGB3 (0.49) | ALDH1A1MAPK1L3MBTL1GLA | |
| SCHEMBL8812645 | 0.73 | GLA (0.52) | ALDH1A1MAPK1L3MBTL1HTR2CGLA | |
| SCHEMBL1177836 | 0.73 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1NOTUMLMNA | |
| SCHEMBL25186094 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1GLANOTUM | |
| SCHEMBL335071 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL9265342 | 0.72 | KLK7 (0.60) | ALDH1A1MAPK1L3MBTL1LMNATDP1 | |
| SCHEMBL7495579 | 0.72 | KLK7 (0.57) | ALDH1A1MAPK1L3MBTL1NOTUMLMNA | |
| SCHEMBL22012840 | 0.71 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1GLANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085118-A1 | PYRIDINE COMPOUNDS AND THEIR USE AS P2Y12 ANTAGONISTS. | ASTRAZENECA AB (SE) | 2008-07-17 | — | — | WO | disclosed |