Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | REN | P00797 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749586 | 0.89 | DYRK1A (0.35) | DYRK1AGAAHEXAHEXBMAOA | |
| SCHEMBL4749301 | 0.82 | MAOA (0.34) | DYRK1AGAADYRK2DYRK1BDHFR | |
| SCHEMBL4749246 | 0.77 | DYRK1A (0.36) | DYRK1AGAAMAOAMAOBPGR | |
| SCHEMBL4746992 | 0.77 | MAOA (0.34) | DYRK1AGAAMAOAMAOBPGR | |
| SCHEMBL4749400 | 0.71 | MAOA (0.35) | GAAMAOAMAOBPGR | |
| SCHEMBL4072001 | 0.71 | BACE1 (0.40) | GAAMAOAMAOB | |
| SCHEMBL4064490 | 0.71 | GLP1R (0.34) | HEXAHEXBMAOAMAOB | |
| SCHEMBL4070347 | 0.71 | GAA (0.43) | DYRK1AGAADYRK2DYRK1BMAOA | |
| SCHEMBL4749132 | 0.71 | MAOA (0.37) | GAAMAOAMAOBPGR | |
| Hydrochloric Acid SCHEMBL4250086 | 0.70 | MAOA (0.35) | GAAMAOAMAOBPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |