Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747016 | 0.82 | MAOA (0.34) | MAOAMAOBPGR | |
| SCHEMBL4808073 | 0.77 | DYRK1A (0.39) | DYRK1AMAOAMAOBPGRGAA | |
| SCHEMBL4749586 | 0.74 | DYRK1A (0.35) | DYRK1AMAOAMAOBGAANOS3 | |
| SCHEMBL18238925 | 0.73 | MAOA (0.36) | DYRK1AMAOAMAOB | |
| SCHEMBL4786331 | 0.72 | PKM (0.42) | GAA | |
| SCHEMBL4786333 | 0.71 | CA1 (0.33) | MAOAMAOB | |
| SCHEMBL4070347 | 0.71 | GAA (0.43) | DYRK1AMAOAMAOBPGRGAA | |
| SCHEMBL4069470 | 0.71 | MAOA (0.37) | MAOAMAOBPGRGAA | |
| SCHEMBL4746992 | 0.71 | MAOA (0.34) | DYRK1AMAOAMAOBPGRGAA | |
| SCHEMBL4063663 | 0.71 | MAOA (0.31) | MAOAMAOBPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |