Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | UNG | P13051 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PGK1 | P00558 | 2/20 | 0.41 |
| ▸ | PGK2 | P07205 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950119 | 0.87 | ALDH1A1 (0.48) | ALDH1A1UNGCYP2A6PGK1PGK2 | |
| SCHEMBL10490641 | 0.79 | ALDH1A1 (0.41) | ALDH1A1UNGCYP2A6PGK1PGK2 | |
| SCHEMBL1263688 | 0.78 | TP53 (0.48) | ALDH1A1TSHRPGK1PGK2PTGS2 | |
| SCHEMBL4951093 | 0.78 | ALDH1A1 (0.54) | ALDH1A1UNGCYP2A6SRCTRIM24 | |
| SCHEMBL31124696 | 0.78 | ALDH1A1 (0.48) | ALDH1A1UNGCYP2A6PGK1PGK2 | |
| SCHEMBL4073513 | 0.78 | UNG (0.48) | ALDH1A1UNGCYP2A6PGK1PGK2 | |
| SCHEMBL4952311 | 0.78 | ALDH1A1 (0.48) | ALDH1A1UNGCYP2A6SRCTRIM24 | |
| SCHEMBL2937253 | 0.78 | ALDH1A1 (0.48) | ALDH1A1UNGCYP2A6SRCTRIM24 | |
| SCHEMBL727874 | 0.78 | TYR (0.56) | ALDH1A1UNGCYP2A6SRCTRIM24 | |
| SCHEMBL30291836 | 0.78 | TYR (0.56) | ALDH1A1UNGCYP2A6SRCTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8323621-B2 | site-directed delivery of contrast agent; brain or breast cancer; 1,4,7,10 tetraazacyclododecane having variable chelating ions, phosphoester chains, and light harvesting moieties for changing imaging methods; conjugated to high affinity PBR ligand PK11195; bound to a PVA or a PEG delivery vehicle | VANDERBILT UNIVERSITY (US) | 2012-12-04 | — | — | US | disclosed |
| US-20080241873-A1 | MULTI-USE MULTIMODAL IMAGING CHELATES | BORNHOP DARRYL J | 2008-10-02 | — | — | US | disclosed |
| US-20080241074-A1 | MULTI-USE MULTIMODAL IMAGING CHELATES | VANDERBILT UNIVERSITY | 2008-10-02 | — | — | US | disclosed |
| US-7338651-B2 | Multi-use multimodal imaging chelates | TEXAS TECH UNIVERSITY SYSTEM (US) | 2008-03-04 | — | — | US | disclosed |
| EP-1429783-A4 | MULTI-USE MULTIMODAL IMAGING CHELATES | UNIV TEXAS TECH (US) | 2006-08-09 | — | — | EP | disclosed |
| EP-1429783-A2 | MULTI-USE MULTIMODAL IMAGING CHELATES | TEXAS TECH UNIVERSITY (US) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003020701-A9 | MULTI-USE MULTIMODAL IMAGING CHELATES | UNIV TEXAS TECH (US) | 2003-09-12 | — | — | WO | disclosed |
| US-20030129579-A1 | Formed from 1,4,7,10 tetraazacyclododecane having varying chelating ions, phosphoester chains, and light harvesting moieties. | VANDERBILT UNIVERSITY | 2003-07-10 | — | — | US | disclosed |
| WO-2003020701-A2 | MULTI-USE MULTIMODAL IMAGING CHELATES | TEXAS TECH UNIVERSITY (US) | 2003-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080241074-A1 | MULTI-USE MULTIMODAL IMAGING CHELATES | PCNA, CLTC, CLTB | ALDH1A1 3987/4885UNG 1571/4885CYP2A6 4458/4885 |
| US-20030129579-A1 | Formed from 1,4,7,10 tetraazacyclododecane having varying chelating ions, phosphoester chains, and light harvesting moieties. | PCNA, CLTC, PHOSPHO1 | ALDH1A1 3803/4885UNG 2226/4885CYP2A6 4078/4885 |
| US-20080241873-A1 | MULTI-USE MULTIMODAL IMAGING CHELATES | PCNA, CLTC, CLTB | ALDH1A1 3987/4885UNG 1571/4885CYP2A6 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.