Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.41 |
| ▸ | FDPS | P14324 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL661554 | 0.83 | KMT2A (0.41) | PDE4APDE4BPDE4DPDE4CHPGD | |
| SCHEMBL4808673 | 0.80 | PDE4A (0.46) | PDE4APDE4BFDPSPDE4DPDE4C | |
| SCHEMBL4808684 | 0.69 | PDE4A (0.42) | PDE4APDE4BFDPSPDE4DPDE4C | |
| SCHEMBL11951574 | 0.68 | PDE4A (0.44) | PDE4APDE4BFDPSPDE4DTNF | |
| SCHEMBL462345 | 0.66 | FDPS (0.55) | FDPSLMNATP53HPGDHSD17B10 | |
| SCHEMBL10080328 | 0.66 | SMPD1 (0.48) | PDE4APDE4BFDPSPDE4DPDE4C | |
| SCHEMBL7333971 | 0.65 | SMPD1 (0.50) | PDE4APDE4BFDPSPDE4DPDE4C | |
| SCHEMBL2999857 | 0.64 | PDE4D (0.49) | PDE4APDE4BPDE4DPDE4CTNF | |
| SCHEMBL22420344 | 0.64 | ALOX5 (0.46) | PDE4APDE4BFDPSLMNA | |
| SCHEMBL16955884 | 0.64 | FDPS (0.48) | FDPSTP53HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124878-A1 | NON-STEROIDAL COMPOUNDS | CRYPTOPHARMA PTY LTD (AU) | 2008-10-23 | — | — | WO | disclosed |