Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.46 |
| ▸ | FDPS | P14324 | 3/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL661555 | 0.83 | PDE4B (0.45) | PDE4APDE4BPDE4DPDE4CHPGD | |
| SCHEMBL4808664 | 0.80 | PDE4A (0.43) | PDE4APDE4BPDE4DPDE4CFDPS | |
| SCHEMBL4808684 | 0.74 | PDE4A (0.42) | PDE4APDE4BPDE4DPDE4CFDPS | |
| SCHEMBL11951574 | 0.72 | PDE4A (0.44) | PDE4APDE4BPDE4DFDPSTNF | |
| SCHEMBL10102164 | 0.71 | ACHE (0.36) | PDE4APDE4BPDE4DPDE4CHPGD | |
| SCHEMBL10080328 | 0.69 | SMPD1 (0.48) | PDE4APDE4BPDE4DPDE4CFDPS | |
| SCHEMBL462345 | 0.69 | FDPS (0.55) | FDPSHPGDHSD17B10 | |
| SCHEMBL661285 | 0.69 | PDE4D (0.46) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL10107050 | 0.68 | ESR2 (0.44) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7333971 | 0.68 | SMPD1 (0.50) | PDE4APDE4BPDE4DPDE4CFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124878-A1 | NON-STEROIDAL COMPOUNDS | CRYPTOPHARMA PTY LTD (AU) | 2008-10-23 | — | — | WO | disclosed |