Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 2/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4811723 | 0.84 | F2 (0.43) | PLA2G4APPARGF2F10PRSS1 | |
| SCHEMBL4812742 | 0.79 | F2 (0.46) | CPT1ACPT2CPT1BPLA2G4AF2 | |
| SCHEMBL4811788 | 0.74 | CNR2 (0.41) | PLA2G4APPARGF2F10 | |
| SCHEMBL4626809 | 0.74 | ICMT (0.47) | CYSLTR1CYSLTR2F2PRSS1 | |
| SCHEMBL6393014 | 0.74 | PLA2G2A (0.41) | PLA2G4APPARGF2F10 | |
| SCHEMBL4626912 | 0.74 | GPR84 (0.48) | CPT1ACPT1BF2F10PRSS1 | |
| SCHEMBL4808748 | 0.74 | ALDH1A1 (0.43) | PLA2G4APPARGF2F10PRSS1 | |
| SCHEMBL4657400 | 0.73 | F10 (0.44) | CYSLTR1CYSLTR2F2F10PRSS1 | |
| SCHEMBL4811885 | 0.73 | F2 (0.41) | PLA2G4APPARGF2F10PRSS1 | |
| SCHEMBL4809426 | 0.73 | PLA2G2A (0.52) | F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417063-B2 | Bicyclic heterocycles useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-08-26 | — | — | US | claimed |