Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 2/20 | 0.39 |
| ▸ | LDHB | P07195 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5516712 | 1.00 | HDAC1 (0.44) | HDAC1CA12CA1MMP2MEN1 | |
| SCHEMBL14509042 | 0.89 | HDAC1 (0.44) | HDAC1CA12CA1MMP2MEN1 | |
| SCHEMBL8996294 | 0.87 | NPSR1 (0.46) | HDAC1CA12CA1MMP2MEN1 | |
| SCHEMBL8996269 | 0.87 | NPSR1 (0.46) | HDAC1CA12CA1MMP2MEN1 | |
| SCHEMBL3264820 | 0.87 | HDAC1 (0.43) | HDAC1CA12CA1MMP2MEN1 | |
| SCHEMBL3264823 | 0.87 | HDAC1 (0.43) | HDAC1CA12CA1MMP2MEN1 | |
| SCHEMBL8996267 | 0.87 | HDAC1 (0.43) | HDAC1CA12CA1MMP2MEN1 | |
| SCHEMBL14534749 | 0.86 | HDAC1 (0.46) | HDAC1CA12CA1MMP2MEN1 | |
| SCHEMBL1734544 | 0.86 | CA12 (0.46) | HDAC1CA12CA1MMP2MEN1 | |
| SCHEMBL1734546 | 0.86 | CA12 (0.46) | HDAC1CA12CA1MMP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351849-B2 | Process for producing optically active β-amino acid derivatives | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2008-04-01 | — | — | US | disclosed |
| US-7223859-B2 | Method for producing (R)-3-[4-(trifluoromethyl) phenylamino]-pentanoic acid amide derivative | PFIZER INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-20060205968-A1 | Process for producing optically active beta-amino acid derivatives | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-09-14 | — | — | US | disclosed |
| EP-1656342-A2 | PROCESS FOR PRODUCING OPTICALLY ACTIVE BETA-AMINO ACID DERIVATIVES | Takasago International Corporation (JP) | 2006-05-17 | — | — | EP | disclosed |
| EP-1604975-A1 | PROCESSES FOR PRODUCTION OF (R)-3- 4-(TRIFLUOROMETHYL)- PHEN YLAMINO PENTANAMIDE DERIVATIVES | KANEKA CORPORATION (JP) | 2005-12-14 | — | — | EP | disclosed |
| WO-2005016866-A2 | PROCESS FOR PRODUCING OPTICALLY ACTIIVE BETA-AMINO ACID DERIVATIVES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-02-24 | — | — | WO | disclosed |
| US-20040199005-A1 | Method for producing (R) -3- [4- (trifluoromethyl) phenylamino] -pentanoic acid amide derivative | KANEKA CORPORATION (JP) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040199005-A1 | Method for producing (R) -3- [4- (trifluoromethyl) phenylamino] -pentanoic acid amide derivative | CETP, PCTP, MTTP | HDAC1 1450/4885CA12 3484/4885CA1 2155/4885 |
| US-20060205968-A1 | Process for producing optically active beta-amino acid derivatives | BCAT1, ALAD, AADAT | HDAC1 4244/4885CA12 934/4885CA1 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.