SCHEMBL4812459

SCHEMBL4812459

CCC(Cc1ccc(N(C)C)cc1)(C(=O)c1ccccc1)N(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.47
HPGD P15428 4/20 0.47
NPC1 O15118 2/20 0.47
KMT2A Q03164 6/20 0.44
MEN1 O00255 3/20 0.44
ALDH1A1 P00352 9/20 0.43
MAPT P10636 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
LMNA P02545 2/20 0.42
KDM4E B2RXH2 3/20 0.39
ALOX15 P16050 2/20 0.39
CYP3A4 P08684 1/20 0.39
KCNK3 O14649 1/20 0.39
GFER P55789 1/20 0.39
HDAC1 Q13547 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
GAA P10253 2/20 0.38
TP53 P04637 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL58499 0.94 KMT2A (0.51) RAB9AHPGDNPC1KMT2AMEN1
SCHEMBL8631398 0.92 ACHE (0.43) RAB9AHPGDNPC1KMT2AMEN1
SCHEMBL4650526 0.90 RIPK1 (0.43) RAB9ANPC1KMT2AMEN1SMN1; SMN2
Benzene SCHEMBL28672020 0.90 RIPK1 (0.43) RAB9ANPC1KMT2AMEN1SMN1; SMN2
SCHEMBL4651748 0.87 NPC1 (0.41) RAB9AHPGDNPC1KMT2AMEN1
SCHEMBL8900778 0.87 KMT2A (0.55) RAB9AHPGDNPC1KMT2AMEN1
SCHEMBL28096104 0.86 CYP2D6 (0.39) KMT2AMEN1SMN1; SMN2KDM4ECYP3A4
Fluoride SCHEMBL28209043 0.86 NPC1 (0.41) RAB9AHPGDNPC1KMT2AMEN1
SCHEMBL8899130 0.84 NPSR1 (0.41) RAB9AHPGDNPC1KMT2AMEN1
SCHEMBL4651502 0.84 ACHE (0.48) RAB9ANPC1KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7365104-B2 Light curable articles containing azinium salts EASTMAN KODAK COMPANY (US) 2008-04-29 US disclosed
US-20060223902-A1 Light curable articles containing azinium salts EASTMAN KODAK COMPANY 2006-10-05 US disclosed
US-6242057-B1 GENERATING PHOTOINITIATORS KIMBERLY-CLARK WORLDWIDE, INC. 2001-06-05 US disclosed
EP-0767803-B1 METHOD OF GENERATING A REACTIVE SPECIES AND APPLICATIONS THEREFOR KIMBERLY CLARK CO (US) 2000-08-23 EP disclosed
US-6090236-A POLYMERIC WEB COATED WITH IRRADIATION-CURED RESIN PHOTOINITIATED WITH PHOTOINITIATOR HAVING A COVALENTLY BOUND SENSITIZING MOIETY SPECIFIC TO WAVELENGTH OF CURING RADIATION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2000-07-18 US disclosed
US-6071979-A TO GENERATE PHOTOINITIATORS FOR POLYMERIZING UNSATURATED MONOMERS AND CURING AN UNSATURATED OLIGOMER/MONOMER MIXTURE KIMBERLY-CLARK WORLDWIDE, INC. (US) 2000-06-06 US disclosed
EP-0994125-A1 Method of generating a reactive species and applications thereof KIMBERLY-CLARK CORPORATION (US) 2000-04-19 EP disclosed
US-6008268-A A PHOTOREACTOR COMPOUND COMPRISING A WAVELENGTH-SPECIFIC SENSITIZER MOIETY COVALENTLY BONDED TO TWO REACTIVE SPECIES-GENERATING PHOTOINITIATOR MOIETIES; PHOTOPOLYMERIZATION; PHOTOCURING; LOW-ENERGY LAMPS KIMBERLY-CLARK WORLDWIDE, INC. (US) 1999-12-28 US disclosed
US-5811199-A Adhesive compositions containing a photoreactor composition KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-09-22 US disclosed
US-5798015-A Method of laminating a structure with adhesive containing a photoreactor composition KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-08-25 US disclosed
US-5709955-A LAMINATION, PHOTOREACTOR WITH WAVELENGTH-SPECIFIC SENSITIZER BONDED TO PHOTOINITIATOR KIMBERLY-CLARK CORPORATION (US) 1998-01-20 US disclosed
US-5685754-A FIBERS, WEBS, PHOTOSENSITIZER AND PHOTOINITIATOR COVALENTLY BONDED AS A PHOTOREACTOR KIMBERLY-CLARK CORPORATION (US) 1997-11-11 US disclosed
US-5686503-A PHOTOINITIATORS KIMBERLY-CLARK CORPORATION (US) 1997-11-11 US disclosed