Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651504 | 0.95 | ACHE (0.51) | ACHECES2CES1MEN1KMT2A | |
| SCHEMBL8631398 | 0.94 | ACHE (0.43) | ACHECES2CES1MEN1KMT2A | |
| SCHEMBL7943207 | 0.91 | LMNA (0.47) | ACHEMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL8897587 | 0.89 | ACHE (0.57) | ACHECES2CES1MEN1KMT2A | |
| Benzene SCHEMBL28672020 | 0.87 | RIPK1 (0.43) | CES2CES1MEN1KMT2ARAB9A | |
| SCHEMBL4650526 | 0.87 | RIPK1 (0.43) | CES2CES1MEN1KMT2ARAB9A | |
| SCHEMBL8899530 | 0.87 | ACHE (0.51) | ACHECES2CES1MEN1KMT2A | |
| SCHEMBL5590415 | 0.86 | L3MBTL1 (0.45) | ACHEMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL14156794 | 0.85 | NPY5R (0.47) | ACHEMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL4651748 | 0.85 | NPC1 (0.41) | CES2CES1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968965-A2 | A METHOD FOR THE PREPARATION OF (S)-N-METHYL-3-(l-NAPHTHYLOXY)-3-(2-THIENYL)PROPYLAMINE HYDROCHLORIDE (DULOXETINE) | Zentiva, a.s. (CZ) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007076733-A2 | A METHOD FOR THE PREPARATION OF (S)-N-METΗYL-3-(l-NAPHTHYLOXY)-3-(2-THIENYL)PROPYLAMINE HYDROCHLORIDE (DULOXETINE) | ZENTIVA A.S. (CZ) | 2007-07-12 | — | — | WO | disclosed |
| US-6887347-B2 | Cellulose fibers comprising radiation activatable resin formalities | THE PROCTER AND GAMBLE COMPANY (US) | 2005-05-03 | — | — | US | disclosed |
| US-20040140070-A1 | Cellulose fibers comprising radiation activatable resin formalities | THE PROCTER & GAMBLE COMPANY | 2004-07-22 | — | — | US | disclosed |