SCHEMBL4813312

SCHEMBL4813312

CC(C)NCCNc1ccc(-c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.45
FNTB P49356 1/20 0.45
CTSK P43235 3/20 0.43
MAPT P10636 3/20 0.42
ALDH1A1 P00352 3/20 0.42
TAAR1 Q96RJ0 1/20 0.41
HRH1 P35367 1/20 0.40
KAT2B Q92831 1/20 0.40
NPC1 O15118 1/20 0.40
MITF O75030 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
FFAR1 O14842 1/20 0.39
HDAC1 Q13547 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4813329 0.94 MAPT (0.48) FNTAFNTBCTSKMAPTALDH1A1
SCHEMBL18236672 0.88 MAPT (0.54) MAPTALDH1A1KAT2BHTTRAB9A
SCHEMBL2421711 0.83 CTSK (0.48) FNTAFNTBCTSKALDH1A1HRH1
SCHEMBL15083052 0.79 MAPT (0.46) MAPTALDH1A1KAT2BHTTGAA
SCHEMBL14387512 0.77 MAPT (0.45) MAPTALDH1A1KAT2BHTTRAB9A
SCHEMBL10850136 0.77 MAPT (0.45) CTSKMAPTALDH1A1NPC1RAB9A
SCHEMBL8260133 0.76 ALDH1A1 (0.48) FNTAFNTBMAPTALDH1A1NPC1
SCHEMBL22267929 0.76 SIGMAR1 (0.59) ALDH1A1TAAR1HTT
SCHEMBL14558232 0.75 POLB (0.45) FNTAFNTBMAPTALDH1A1MITF
SCHEMBL7163224 0.75 FNTA (0.58) FNTAFNTBCTSKMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7437108-B2 Developing roller for electrographic apparatus including a base rubber, a conductive polymer, a conductive carbon black and a binder resin and electrographic apparatus containing the developing roller SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-10-14 US disclosed
US-20050220502-A1 Developing roller for electrographic apparatus and electrographic apparatus comprising the same SAMSUNG ELECTRONICS CO., LTD. 2005-10-06 US disclosed