Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649135 | 0.74 | ALDH1A1 (0.43) | HPGDMAPTHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL11238876 | 0.69 | ALDH1A1 (0.40) | HPGDMAPTHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL27608364 | 0.69 | LGMN (0.42) | MAPTHSD17B10MAPK1ALDH1A1PRKDC | |
| SCHEMBL10706814 | 0.68 | MAPT (0.47) | HPGDMAPTHSD17B10ALDH1A1PRKDC | |
| SCHEMBL19381145 | 0.67 | LGMN (0.64) | HPGDMAPTHSD17B10ALDH1A1NPC1 | |
| SCHEMBL26472755 | 0.66 | MAPT (0.62) | HPGDMAPTHSD17B10ALDH1A1NPC1 | |
| SCHEMBL30861221 | 0.66 | MAPT (0.62) | HPGDMAPTHSD17B10ALDH1A1NPC1 | |
| SCHEMBL11699370 | 0.66 | CCR5 (0.52) | HPGDMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL7114823 | 0.66 | ALDH1A1 (0.43) | HPGDMAPTHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL14283828 | 0.66 | MAPT (0.46) | MAPTHSD17B10MAPK1ALDH1A1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321054-B2 | Method of producing poly(ortho-methylphenol) | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-01-22 | — | — | US | disclosed |
| US-20070197832-A1 | METHOD OF PRODUCING POLY(ORTHO-METHYLPHENOL) | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197832-A1 | METHOD OF PRODUCING POLY(ORTHO-METHYLPHENOL) | COMT, HPD, KDM8 | HPGD 609/4885MAPT 1486/4885HSD17B10 1686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.