Sugi Predict

Sugi Predict / Compounds / SCHEMBL4813371

SCHEMBL4813371

SCHEMBL4813371

CCCCCC1SCC2NC(=O)NC21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HLCS P50747 6/20 1.00
▸ TDP1 Q9NUW8 6/20 0.67
▸ MEN1 O00255 1/20 0.67
▸ ABL1 P00519 1/20 0.67
▸ LMNA P02545 1/20 0.67
▸ PKM P14618 1/20 0.67
▸ IDE P14735 1/20 0.67
▸ MAPK1 P28482 1/20 0.67
▸ KMT2A Q03164 1/20 0.67
▸ RIN1 Q13671 1/20 0.67
▸ L3MBTL1 Q9Y468 1/20 0.67
▸ CA12 O43570 6/20 0.47
▸ CA1 P00915 6/20 0.47
▸ CA2 P00918 6/20 0.47
▸ CA9 Q16790 6/20 0.47
▸ F2 P00734 1/20 0.44
▸ PRSS1 P07477 1/20 0.44
▸ PRSS2 P07478 1/20 0.44
▸ PRSS3 P35030 1/20 0.44
▸ TPSAB1 Q15661 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10038443 1.00 HLCS (1.00) HLCSTDP1MEN1ABL1LMNA
SCHEMBL4813368 1.00 HLCS (1.00) HLCSTDP1MEN1ABL1LMNA
SCHEMBL423924 1.00 HLCS (1.00) HLCSTDP1MEN1ABL1LMNA
SCHEMBL21769329 1.00 HLCS (1.00) HLCSTDP1MEN1ABL1LMNA
SCHEMBL11248300 1.00 HLCS (1.00) HLCSTDP1MEN1ABL1LMNA
SCHEMBL11248303 1.00 HLCS (1.00) HLCSTDP1MEN1ABL1LMNA
SCHEMBL19249123 0.98 HLCS (1.00) HLCSTDP1MEN1ABL1LMNA
SCHEMBL21348602 0.98 HLCS (1.00) HLCSTDP1MEN1ABL1LMNA
SCHEMBL10286412 0.98 HLCS (1.00) HLCSTDP1MEN1ABL1LMNA
SCHEMBL12654818 0.98 HLCS (1.00) HLCSTDP1MEN1ABL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021105843-A1 BIOTIN-CONTAINING MONOMERS AND ARTICLES FORMED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-06-03 — — WO disclosed
US-10975120-B2 Site-specific chemoenzymatic protein modifications NOVARTIS AG (CH) 2021-04-13 — — US disclosed
WO-2021041710-A1 SYSTEMS AND METHODS FOR PERFORMING ANTIMICROBIAL SUSCEPTIBILITY TESTING SeLux Diagnostics, Inc. (US) 2021-03-04 — — WO disclosed
US-20190300570-A1 SITE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2019-10-03 — — US disclosed
WO-2019173499-A1 17-BETA-HYDROXYWITHANOLIDES AND USE THEREOF IN TREATING CANCER THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2019-09-12 — — WO disclosed
WO-2019023501-A1 UNIVERSAL ABT COMPOUNDS AND USES THEREOF KLEO PHARMACEUTICALS, INC. (US) 2019-01-31 — — WO disclosed
WO-2017218796-A1 METABOLIC LABELING AND MOLECULAR ENHANCEMENT OF BIOLOGICAL MATERIALS USING BIOORTHOGONAL REACTIONS OTT HARALD C (US) 2017-12-21 — — WO disclosed
WO-2017143059-A1 MAX BINDERS AS MYC MODULATORS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-08-24 — — WO disclosed
US-20170233405-A1 MAX BINDERS AS MYC MODULATORS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2017-08-17 — — US disclosed
US-20160237116-A1 SITE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS NOVARTIS AG 2016-08-18 — — US disclosed
US-6648930-B2 For use as foods, animal feeds, and in producing ethanol by combining the corn meal with water and alpha-amylase enzyme, incubating, fermenting RENESSEN LLC 2003-11-18 — — US disclosed
US-20030194788-A1 Method for producing fermentation-based products from high oil corn RENESSEN, LLC. 2003-10-16 — — US disclosed
US-20030180897-A1 Fermentation-based products from corn and method RENESSEN LLC (US) 2003-09-25 — — US disclosed
US-6610867-B2 Cracking, conditioning, solvent extracting corn is not flaked during processing RENESSEN LLC 2003-08-26 — — US disclosed
EP-1307110-A2 PRODUCTS COMPRISING CORN OIL AND CORN MEAL OBTAINED FROM HIGH OIL CORN Renessen LLC (US) 2003-05-07 — — EP disclosed
US-20030083512-A1 Corn oil processing and products comprising corn oil and corn meal obtained from corn RENESSEN, LLC. (US) 2003-05-01 — — US disclosed
WO-2003015535-A1 PRODUCTS COMPRISING CORN OIL AND CORN MEAL OBTAINED FROM CORN RENESSEN LLC (US) 2003-02-27 — — WO disclosed
US-20020193617-A1 Products comprising corn oil and corn meal obtained from high oil corn RENESSEN LLC 2002-12-19 — — US disclosed
US-20020151733-A1 Products comprising corn oil and corn meal obtained from corn RENESSEN LLC 2002-10-17 — — US disclosed
WO-2002014459-A2 PRODUCTS COMPRISING CORN OIL AND CORN MEAL OBTAINED FROM HIGH OIL CORN RENESSEN LLC (US) 2002-02-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190300570-A1 SITE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS PTMS, TGM3, TGM1 HLCS 147/4885TDP1 2938/4885MEN1 2255/4885
US-20160237116-A1 SITE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS PTMS, TGM3, TGM1 HLCS 147/4885TDP1 2938/4885MEN1 2255/4885
US-20170233405-A1 MAX BINDERS AS MYC MODULATORS AND USES THEREOF MYC, MYCBP, MYCBP2 HLCS 1990/4885TDP1 2534/4885MEN1 78/4885
US-10975120-B2 Site-specific chemoenzymatic protein modifications PTMS, TGM3, TGM1 HLCS 147/4885TDP1 2938/4885MEN1 2255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.