Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HLCS | P50747 | 6/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | IDE | P14735 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10038443 | 1.00 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL4813368 | 1.00 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL21769329 | 1.00 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL4813371 | 1.00 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL11248300 | 1.00 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL11248303 | 1.00 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL19249123 | 0.98 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL21348602 | 0.98 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL10286412 | 0.98 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL12654818 | 0.98 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145785-A1 | BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF EXHIBITING AN ANTI-GERIATRIC EFFECT | ФАРБЕР, Борис Славинович | 2021-07-22 | — | — | WO | disclosed |
| WO-2020132588-A1 | COMBINATION THERAPY OF ARMS AND NATURAL KILLER CELLS | KLEO PHARMACEUTICALS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| US-20120065406-A1 | Improved Preparation Method for D-Biotin | ZHEJIANG MEDICINE CO., LTD., XINCHANG PHARMACEUTICAL FACTORY (CN) | 2012-03-15 | — | — | US | disclosed |
| US-20110189692-A1 | ASSAY FOR PATHOGENIC CONFORMERS | NOVARTIS AG | 2011-08-04 | — | — | US | disclosed |
| US-20070087972-A1 | Prion-specific peptoid reagents | NOVARTIS AG (CH) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065406-A1 | Improved Preparation Method for D-Biotin | ACSL3, SQLE, BTD | HLCS 61/4885TDP1 4732/4885MEN1 3736/4885 |
| US-20070087972-A1 | Prion-specific peptoid reagents | PRNP, PARL, PCNP | HLCS 714/4885TDP1 1545/4885MEN1 2738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.