Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HLCS | P50747 | 6/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | IDE | P14735 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769329 | 1.00 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL4813368 | 1.00 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL11248303 | 1.00 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL4813371 | 1.00 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL11248300 | 1.00 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL423924 | 1.00 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL10286412 | 0.98 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL19249123 | 0.98 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL21348602 | 0.98 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL12654818 | 0.98 | HLCS (1.00) | HLCSTDP1MEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147153-A1 | PEPTIDE-HISTIDINAL CONJUGATES AS AN ANTI-MALARIAL AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2024-07-11 | — | — | WO | disclosed |
| US-20230330240-A1 | TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS | BIOHAVEN THERAPEUTICS LTD (US) | 2023-10-19 | — | — | US | disclosed |
| US-11654120-B2 | Composition for treating skin conditions | OLLIE'S HEALTH, LLC (US) | 2023-05-23 | — | — | US | disclosed |
| US-20230028880-A1 | CD38-BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. | 2023-01-26 | — | — | US | disclosed |
| WO-2021145785-A1 | BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF EXHIBITING AN ANTI-GERIATRIC EFFECT | ФАРБЕР, Борис Славинович | 2021-07-22 | — | — | WO | disclosed |
| US-20200390895-A1 | UNIVERSAL ABT COMPOUNDS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. | 2020-12-17 | — | — | US | disclosed |
| WO-2020185610-A1 | NEW TECHNOLOGY TO CONJUGATE THE TACCALONOLIDE MICROTUBULE STABILIZERS WITH LINKERS/PAYLOADS | DU LIN (US) | 2020-09-17 | — | — | WO | disclosed |
| WO-2020132588-A1 | COMBINATION THERAPY OF ARMS AND NATURAL KILLER CELLS | KLEO PHARMACEUTICALS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2019023501-A1 | UNIVERSAL ABT COMPOUNDS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-01-31 | — | — | WO | disclosed |
| US-20180185321-A1 | TALC-BOUND COMPOSITIONS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-07-05 | — | — | US | disclosed |
| US-20150044672-A1 | STREPTAVIDIN COMPLEXES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-02-12 | — | — | US | disclosed |
| US-20120083599-A1 | Biomolecular Labelling Using Multifunctional Biotin Analogues | UNIVERSITY OF NOTTINGHAM (GB) | 2012-04-05 | — | — | US | disclosed |
| US-8110207-B2 | Pigmentation-regulating compounds | LIPOTEC, S.A. (ES) | 2012-02-07 | — | — | US | disclosed |
| US-20100247587-A1 | PIGMENTATION-REGULATING COMPOUNDS | LIPOTEC, S.A. (ES) | 2010-09-30 | — | — | US | disclosed |
| US-20100048642-A1 | METHODS FOR TREATING COGNITIVE DISORDERS | ALLERGAN, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| US-20100048642-A1 | METHODS FOR TREATING COGNITIVE DISORDERS | ALLERGAN, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| WO-2007039581-A1 | IMIDAZOLYL-SUBSTITUTED DIAZABENZOPHENONE COMPOUNDS | NYCOMED GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039580-A1 | IMIDAZOLYL-SUBSTITUTED BENZOPHENONE COMPOUNDS | NYCOMED GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039578-A1 | IMIDAZOLYL-SUBSTITUTED AZABENZOPHENONE COMPOUNDS | NYCOMED GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |
| US-4130713-A | Biotin intermediates | HOFFMANN-LA ROCHE INC. (US) | 1978-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083599-A1 | Biomolecular Labelling Using Multifunctional Biotin Analogues | BTD, URB2, RAET1L | HLCS 7/4885TDP1 4767/4885MEN1 3602/4885 |
| US-20180185321-A1 | TALC-BOUND COMPOSITIONS AND USES THEREOF | SSB, UACA, TTR | HLCS 456/4885TDP1 624/4885MEN1 667/4885 |
| US-20100247587-A1 | PIGMENTATION-REGULATING COMPOUNDS | TYR, MC1R, MITF | HLCS 451/4885TDP1 4167/4885MEN1 2744/4885 |
| US-20100048642-A1 | METHODS FOR TREATING COGNITIVE DISORDERS | CHAT, SLC18A3, SLC18A2 | HLCS 2929/4885TDP1 734/4885MEN1 4362/4885 |
| US-11654120-B2 | Composition for treating skin conditions | CUTA, DSG1, ERCC1 | HLCS 2980/4885TDP1 194/4885MEN1 3590/4885 |
| US-20200390895-A1 | UNIVERSAL ABT COMPOUNDS AND USES THEREOF | CD47, MCL1, BCL9 | HLCS 303/4885TDP1 1596/4885MEN1 2879/4885 |
| US-20230028880-A1 | CD38-BINDING AGENTS AND USES THEREOF | CD38, CD47, CD2 | HLCS 897/4885TDP1 908/4885MEN1 3315/4885 |
| US-20230330240-A1 | TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS | HAVCR2, ACE2, EPCAM | HLCS 943/4885TDP1 2068/4885MEN1 1907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.