Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18689590 | 0.78 | XDH (0.51) | ALDH1A1SMN1; SMN2HTTRECQLLMNA | |
| Oxypurinol SCHEMBL8256863 | 0.77 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2HTTRECQLLMNA | |
| SCHEMBL4497867 | 0.77 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2HTTRECQLLMNA | |
| SCHEMBL6642975 | 0.77 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2HTTRECQLLMNA | |
| SCHEMBL21169869 | 0.77 | XDH (0.41) | ALDH1A1SMN1; SMN2HTTXDHADORA2A | |
| SCHEMBL2893663 | 0.73 | XDH (0.44) | DYRK1AALDH1A1SMN1; SMN2HTTRECQL | |
| SCHEMBL24097091 | 0.73 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2HTTRECQLLMNA | |
| SCHEMBL18284261 | 0.73 | HTT (0.54) | ALDH1A1SMN1; SMN2HTTRECQLLMNA | |
| SCHEMBL18701487 | 0.73 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2HTTRECQLLMNA | |
| SCHEMBL11353207 | 0.73 | MKNK1 (0.57) | DYRK1AALDH1A1HTTKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266903-B2 | Methods and compositions for detecting antibiotic resistant bacteria | ELITECHGROUP, INC. (US) | 2019-04-23 | — | — | US | claimed |
| US-9932643-B2 | Detection of methicillin-resistant Staphylococcus aureus | ELITECHGROUP B.V. (NL) | 2018-04-03 | — | — | US | claimed |
| EP-3230467-A1 | METHODS AND COMPOSITIONS FOR DETECTING ANTIBIOTIC RESISTANT BACTERIA | ELITechGroup B.V. (NL) | 2017-10-18 | — | — | EP | claimed |
| US-9677142-B2 | Detection of methicillin-resistant Staphylococcus aureus | ELITECHGROUP B.V. (NL) | 2017-06-13 | — | — | US | claimed |
| US-20160168628-A1 | METHODS AND COMPOSITIONS FOR DETECTING ANTIBIOTIC RESISTANT BACTERIA | ELITECHGROUP MDX LLC | 2016-06-16 | — | — | US | claimed |
| WO-2016094162-A1 | METHODS AND COMPOSITIONS FOR DETECTING ANTIBIOTIC RESISTANT BACTERIA | ELITECHGROUP B.V. (NL) | 2016-06-16 | — | — | WO | claimed |
| US-9328384-B2 | Droplet digital PCR with short minor groove probes | ELITECHGROUP B.V. (NL) | 2016-05-03 | — | — | US | claimed |
| US-20150275274-A1 | DETECTION OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS | ELITECH HOLDING B.V. | 2015-10-01 | — | — | US | claimed |
| EP-2714939-B1 | DETECTION OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS | ELITECH HOLDING BV (NL) | 2015-04-15 | — | — | EP | claimed |
| EP-1687609-B1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES INC (US) | 2014-12-10 | — | — | EP | claimed |
| WO-2003062445-A2 | REAL-TIME LINEAR DETECTION PROBES: SENSITIVE 5'-MINOR GROOVE BINDER-CONTAINING PROBES FOR PCR ANALYSIS | EPOCH BIOSCIENCES, INC. (US) | 2003-07-31 | — | — | WO | claimed |
| US-20030113765-A1 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES, INC. (US) | 2003-06-19 | — | — | US | claimed |
| US-6492346-B1 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | EPOCH PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | claimed |
| US-6472153-B1 | COVALENTLY BOUND OLIGONUCLEOTIDE/MINOR GROOVE BINDER/LATENT FLUOROPHORE COMBINATION | EPOCH BIOSCIENCES, INC. | 2002-10-29 | — | — | US | claimed |
| US-20020146690-A1 | OLIGONUCLEOTIDES CONTAINING PYRAZOLO[3,4-D] PYRIMIDINES FOR HYBRIDIZATION AND MISMATCH DISCRIMINATION | ELITECHGROUP B.V. (NL) | 2002-10-10 | — | — | US | claimed |
| EP-1224332-A1 | HYBRIDIZATION-TRIGGERED FLUORESCENT DETECTION OF NUCLEIC ACIDS | Epoch Biosciences, Inc. (US) | 2002-07-24 | — | — | EP | claimed |
| WO-2001031063-A1 | HYBRIDIZATION-TRIGGERED FLUORESCENT DETECTION OF NUCLEIC ACIDS | EPOCH BIOSCIENCES, INC. (US) | 2001-05-03 | — | — | WO | claimed |
| US-6143877-A | FORMING A TRIPLEX BY CONTACTING DUPLEX NUCLEIC ACID HAVING A TARGET SEQUENCE OF PURINE BASES WITH A OLIGONUCLEOTIDE HAVING AT LEAST ONE GUANINE BASE REPLACED BY 6-AMINO-1H-PYRAZOLO(3,4-D)PYRIMIDIN-4(5H)-ONE | EPOCH PHARMACEUTICALS, INC. (US) | 2000-11-07 | — | — | US | claimed |
| US-6127121-A | DISTINGUISHING POLYNUCLEOTIDES WITH RELATED SEQUENCES BY SEPARATELY INCUBATING EACH OF THE POLYNUCLEOTIDES WITH THE MODIFIED OLIGONUCLEOTIDE UNDER HYBRIDIZATION CONDITIONS AND DETERMINING THE DEGREES OF HYBRIDIZATION | EPOCH PHARMACEUTICALS, INC. (US) | 2000-10-03 | — | — | US | claimed |
| WO-1998049180-A1 | TRIPLEX FORMING OLIGONUCLEOTIDES INCLUDING PYRAZOLO(3,4-D)PYRIMIDINE BASES | EPOCH PHARMACEUTICALS, INC. (US) | 1998-11-05 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020146690-A1 | OLIGONUCLEOTIDES CONTAINING PYRAZOLO[3,4-D] PYRIMIDINES FOR HYBRIDIZATION AND MISMATCH DISCRIMINATION | DPYD, DTYMK, DDX41 | DYRK1A 851/4885ALDH1A1 3169/4885SMN1; SMN2 2805/4885 |
| US-20030113765-A1 | Hybridization-triggered fluorescent detection of nucleic acids | DDX21, RNGTT, NOP2 | DYRK1A 3352/4885ALDH1A1 3480/4885SMN1; SMN2 2555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.