Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | PLD1 | Q13393 | 4/20 | 0.35 |
| ▸ | PLD2 | O14939 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | MLNR | O43193 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725678 | 1.00 | HSD11B1 (0.35) | HSD11B1PLD1PLD2HTR1ACHRM1 | |
| SCHEMBL3725056 | 0.88 | HSD11B1 (0.42) | HSD11B1PLD1PLD2HTR1ACHRM1 | |
| SCHEMBL3802467 | 0.82 | HTR1A (0.47) | HSD11B1PLD1PLD2HTR1ACHRM1 | |
| SCHEMBL1838176 | 0.80 | OPRK1 (0.50) | HSD11B1PLD1PLD2HTR1ACHRM1 | |
| SCHEMBL1836260 | 0.80 | OPRK1 (0.50) | HSD11B1PLD1PLD2HTR1ACHRM1 | |
| SCHEMBL3802612 | 0.78 | OPRK1 (0.33) | HSD11B1PLD1PLD2HTR1ACHRM1 | |
| SCHEMBL4896395 | 0.78 | OPRK1 (0.33) | HSD11B1PLD1PLD2HTR1ACHRM1 | |
| SCHEMBL1831703 | 0.77 | OPRM1 (0.47) | PLD1PLD2HTR1ACHRM1DRD2 | |
| SCHEMBL3400375 | 0.77 | OPRM1 (0.47) | PLD1PLD2HTR1ACHRM1DRD2 | |
| SCHEMBL1836591 | 0.77 | PLD1 (0.51) | HSD11B1PLD1PLD2HTR1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | claimed |