SCHEMBL9686180

SCHEMBL9686180

O=C(O)c1ccccc1N1C(=O)C2=C(CC=CC2)C1=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 2/20 0.52
GAA P10253 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ALDH1A1 P00352 6/20 0.47
ALOX15 P16050 1/20 0.47
MYC P01106 3/20 0.45
NR4A1 P22736 1/20 0.45
TDP1 Q9NUW8 3/20 0.42
POLB P06746 1/20 0.42
HSP90AA1 P07900 1/20 0.41
PKM P14618 1/20 0.41
CCR6 P51684 1/20 0.41
ATM Q13315 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TLR9 Q9NR96 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TSHR P16473 1/20 0.39
AKR1C3 P42330 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Phthaloylanthranilic Acid SCHEMBL29549628 0.79 APEX1 (0.71) APEX1GAAL3MBTL1ALDH1A1ALOX15
N-Phthaloylanthranilic Acid SCHEMBL481284 0.79 APEX1 (0.71) APEX1GAAL3MBTL1ALDH1A1ALOX15
SCHEMBL11646227 0.77 APEX1 (0.56) APEX1GAAL3MBTL1ALDH1A1ALOX15
SCHEMBL8889877 0.77 MYC (0.58) APEX1GAAL3MBTL1ALDH1A1ALOX15
Hydrochloric Acid SCHEMBL7461209 0.76 MYC (0.56) APEX1GAAL3MBTL1ALDH1A1ALOX15
SCHEMBL9262225 0.75 GAA (0.55) APEX1GAAL3MBTL1ALDH1A1ALOX15
SCHEMBL481455 0.73 NR1H2 (0.59) APEX1GAAL3MBTL1ALDH1A1ALOX15
SCHEMBL183052 0.73 ALDH1A1 (0.71) APEX1GAAL3MBTL1ALDH1A1ALOX15
SCHEMBL29364136 0.73 ALDH1A1 (0.71) APEX1GAAL3MBTL1ALDH1A1ALOX15
SCHEMBL9516371 0.72 L3MBTL1 (0.60) APEX1GAAL3MBTL1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5086154-A LINEAR AROMATIC POLY(AMIDEIMIDE)S HAVING LATENT MALEIMIDE ENDGROUPS RHONE-POULENC CHIMIE (FR) 1992-02-04 US disclosed