Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 11/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4815151 | 1.00 | ADRB3 (0.39) | ADRB3ADRB1KEAP1NFE2L2PPARG | |
| SCHEMBL4808571 | 0.94 | PPARG (0.43) | ADRB3PPARGPPARA | |
| SCHEMBL4808561 | 0.94 | PPARG (0.43) | ADRB3PPARGPPARA | |
| SCHEMBL4817838 | 0.93 | ADRB3 (0.43) | ADRB3ADRB1PPARGPPARAADAMTS4 | |
| SCHEMBL4817849 | 0.93 | ADRB3 (0.43) | ADRB3ADRB1PPARGPPARAADAMTS4 | |
| SCHEMBL5699357 | 0.89 | ADRB3 (0.42) | ADRB3ADRB1PPARGPPARAADAMTS4 | |
| SCHEMBL5699364 | 0.89 | ADRB3 (0.42) | ADRB3ADRB1PPARGPPARAADAMTS4 | |
| SCHEMBL4818562 | 0.88 | ADRB3 (0.42) | ADRB3ADRB1 | |
| SCHEMBL4818555 | 0.88 | ADRB3 (0.42) | ADRB3ADRB1 | |
| SCHEMBL4814509 | 0.86 | ADRB3 (0.39) | ADRB3ADRB1CYP19A1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417169-B2 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | ADRB2, ADRA2A, ADRA1A | ADRB3 5/4885ADRB1 4/4885KEAP1 3842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.