SCHEMBL481667

SCHEMBL481667

O=C(O)c1ccc(N2C(=O)c3ccccc3C2=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 9/20 1.00
CA12 O43570 9/20 1.00
CA1 P00915 5/20 1.00
SCN2A Q99250 2/20 1.00
CA2 P00918 1/20 1.00
PPARA Q07869 2/20 0.81
RXFP1 Q9HBX9 2/20 0.73
L3MBTL1 Q9Y468 2/20 0.73
KDM4E B2RXH2 2/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
MEN1 O00255 3/20 0.63
KMT2A Q03164 3/20 0.63
GFER P55789 1/20 0.63
POLB P06746 1/20 0.63
APEX1 P27695 1/20 0.63
RECQL P46063 1/20 0.63
CASP6 P55212 1/20 0.63
CTDSP1 Q9GZU7 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
PIM3 Q86V86 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663432 1.00 CA9 (1.00) CA9CA12CA1SCN2ACA2
SCHEMBL16601986 0.87 CA9 (0.77) CA9CA12CA1SCN2ACA2
SCHEMBL10808030 0.86 SCN2A (0.76) CA9CA12CA1SCN2ACA2
SCHEMBL4234750 0.85 CA9 (0.77) CA9CA12CA1SCN2ACA2
SCHEMBL10061703 0.85 CA9 (0.73) CA9CA12CA1SCN2ACA2
SCHEMBL4582684 0.84 CA9 (1.00) CA9CA12CA1SCN2ACA2
SCHEMBL13909220 0.84 CA9 (0.71) CA9CA12CA1SCN2ACA2
SCHEMBL12171938 0.84 CA12 (0.70) CA9CA12CA1SCN2ACA2
SCHEMBL1618163 0.84 KMT2A (0.76) CA9CA12CA1SCN2ACA2
SCHEMBL4649471 0.83 KMT2A (0.78) CA9CA12CA1SCN2ACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138879-A1 MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH KISUMA CHEMICALS B V (NL) 2026-05-21 US claimed
EP-4713340-A2 COMPOSITIONS AND METHODS FOR PEPTIDE-BASED MODULATORS OF HUMAN PAPILLOMAVIRUS ONCOPROTEIN E6 Calico Life Sciences LLC (US) 2026-03-25 EP claimed
EP-4605346-A1 MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH Kisuma Chemicals B.V. (NL) 2025-08-27 EP claimed
WO-2024085755-A1 MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH KISUMA CHEMICALS B.V. (NL) 2024-04-25 WO claimed
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US claimed
EP-0792893-B1 Polyolefins modified with an unsaturated polyfunctional monomer containing an imide group and an ester group POLIMERI EUROPA SPA (IT) 2002-07-17 EP claimed
US-5817720-A GRAFT POLYMERS ENICHEM S.P.A. (IT) 1998-10-06 US claimed
EP-0792893-A2 Polyolefins modified with an unsaturated polyfunctional monomer containing an imide group and an ester group ENICHEM S.p.A. (IT) 1997-09-03 EP claimed
JP-3131631-A None JP disclosed
US-20260138879-A1 MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH KISUMA CHEMICALS B V (NL) 2026-05-21 US disclosed
EP-4713340-A2 COMPOSITIONS AND METHODS FOR PEPTIDE-BASED MODULATORS OF HUMAN PAPILLOMAVIRUS ONCOPROTEIN E6 Calico Life Sciences LLC (US) 2026-03-25 EP disclosed
EP-4605346-A1 MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH Kisuma Chemicals B.V. (NL) 2025-08-27 EP disclosed
WO-2025111511-A2 REVERSIBLY REACTIVE AFFINITY SELECTION MASS SPECTROMETRY AND USES THEREOF CALICO LIFE SCIENCES LLC (US) 2025-05-30 WO disclosed
WO-2024085755-A1 MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH KISUMA CHEMICALS B.V. (NL) 2024-04-25 WO disclosed
EP-0323181-A2 Dispersants resistant to color change E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-05 EP disclosed
US-4812517-A PHENYL AROMATIC ACRYLIC AB BLOCK COPOLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-03-14 US disclosed
US-4812377-A CONTAINS 2,3-DIHYDRO-1,3-DIOXO-1H-ISOINDOLE CARBOXYLIC ACIDS EASTMAN KODAK COMPANY (US) 1989-03-14 US disclosed
EP-0161413-B1 WHOLLY AROMATIC POLYESTERS, PROCESS FOR THEIR PREPARATION AND SHAPED ARTICLES MADE THEREFROM HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-18 EP disclosed
US-4661579-A Completely aromatic polyesters, a process for their preparation and corresponding shaped articles HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-28 US disclosed
EP-0161413-A1 Wholly aromatic polyesters, process for their preparation and shaped articles made therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1985-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138879-A1 MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH LDHA, LDHB, ME2 CA9 10/4885CA12 32/4885CA1 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.